I. Meerovich, I. Kubasova, G. A. Meerovich, A. A. Stratonnikov, S. Demura, A. Brandis, V. Rosenbach‐Belkin, A. Scherz
{"title":"红外光敏剂细菌叶绿素丝氨酸的荧光和光动力学性质","authors":"I. Meerovich, I. Kubasova, G. A. Meerovich, A. A. Stratonnikov, S. Demura, A. Brandis, V. Rosenbach‐Belkin, A. Scherz","doi":"10.1117/12.563144","DOIUrl":null,"url":null,"abstract":"The study is devoted to investigation of fluorescent and photodynamic properties of near-infrared photosensitizer bacteriochlorophyllide-serine. The peculiarities of its fluorescence under different laser excitation conditions, dynamics of concentration and selectivity of accumulation were investigated. Photodynamic therapy of mice and investigation of tissue deoxygenation during tumor irradiation were performed. It was shown that bacteriochlorophyllide-serine is an effective photosensitizer for PDT and fluorescent diagnostics of tumors.","PeriodicalId":194489,"journal":{"name":"International Conference on Laser and Laser Information Technologies","volume":"6 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2004-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Fluorescent and photodynamic properties of infrared photosensitizer bacteriochlorophyllide-serine\",\"authors\":\"I. Meerovich, I. Kubasova, G. A. Meerovich, A. A. Stratonnikov, S. Demura, A. Brandis, V. Rosenbach‐Belkin, A. Scherz\",\"doi\":\"10.1117/12.563144\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The study is devoted to investigation of fluorescent and photodynamic properties of near-infrared photosensitizer bacteriochlorophyllide-serine. The peculiarities of its fluorescence under different laser excitation conditions, dynamics of concentration and selectivity of accumulation were investigated. Photodynamic therapy of mice and investigation of tissue deoxygenation during tumor irradiation were performed. It was shown that bacteriochlorophyllide-serine is an effective photosensitizer for PDT and fluorescent diagnostics of tumors.\",\"PeriodicalId\":194489,\"journal\":{\"name\":\"International Conference on Laser and Laser Information Technologies\",\"volume\":\"6 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2004-06-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Conference on Laser and Laser Information Technologies\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1117/12.563144\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Conference on Laser and Laser Information Technologies","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1117/12.563144","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Fluorescent and photodynamic properties of infrared photosensitizer bacteriochlorophyllide-serine
The study is devoted to investigation of fluorescent and photodynamic properties of near-infrared photosensitizer bacteriochlorophyllide-serine. The peculiarities of its fluorescence under different laser excitation conditions, dynamics of concentration and selectivity of accumulation were investigated. Photodynamic therapy of mice and investigation of tissue deoxygenation during tumor irradiation were performed. It was shown that bacteriochlorophyllide-serine is an effective photosensitizer for PDT and fluorescent diagnostics of tumors.