{"title":"活细胞中的模拟和数字记忆","authors":"Fahim Farzadfard, T. Lu","doi":"10.1145/3109453.3124361","DOIUrl":null,"url":null,"abstract":"The ability to dynamically manipulate information stored in a genome, in a targeted, controlled and recurring manner, confers the great potential to study and engineer living cells. Here, we review some of the recent advances in the development of DNA writers, i.e., molecular devices that enable targeted editing of DNA of living cells, and discuss some of the potential uses of these devices in studying and programming cellular phenotypes.","PeriodicalId":400141,"journal":{"name":"Proceedings of the 4th ACM International Conference on Nanoscale Computing and Communication","volume":"102 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2017-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Analog and digital memory in living cells\",\"authors\":\"Fahim Farzadfard, T. Lu\",\"doi\":\"10.1145/3109453.3124361\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The ability to dynamically manipulate information stored in a genome, in a targeted, controlled and recurring manner, confers the great potential to study and engineer living cells. Here, we review some of the recent advances in the development of DNA writers, i.e., molecular devices that enable targeted editing of DNA of living cells, and discuss some of the potential uses of these devices in studying and programming cellular phenotypes.\",\"PeriodicalId\":400141,\"journal\":{\"name\":\"Proceedings of the 4th ACM International Conference on Nanoscale Computing and Communication\",\"volume\":\"102 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-09-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Proceedings of the 4th ACM International Conference on Nanoscale Computing and Communication\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1145/3109453.3124361\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the 4th ACM International Conference on Nanoscale Computing and Communication","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1145/3109453.3124361","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The ability to dynamically manipulate information stored in a genome, in a targeted, controlled and recurring manner, confers the great potential to study and engineer living cells. Here, we review some of the recent advances in the development of DNA writers, i.e., molecular devices that enable targeted editing of DNA of living cells, and discuss some of the potential uses of these devices in studying and programming cellular phenotypes.
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