磁共振血管造影和有限体积法模拟轻度缩窄主动脉的血流

R. Ghasemiasl, R. Ostadhossein, M. Javadi, S. Hoseinzadeh
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引用次数: 2

摘要

主动脉缩窄是五种主要的先天性心血管疾病之一,占这些疾病的6 - 8%。这项研究旨在模拟一个17岁的男性青少年的血流,他的主动脉降支有三分之一的轻微收缩。采用磁共振血管成像(MRA)和有限体积法(FVM),以及大涡模拟(LES)湍流模型,在主动脉入口处提取域和输入脉动速度信号作为边界条件进行仿真。通过将数值模拟的血流静压与文献中可用的临床测量结果进行比较,验证了结果。在溶液中加入湍流模型,在收缩时心脏正常功能的静压与临床测量结果非常吻合;差异仅为0.39毫米汞柱。因此,本研究证实了模拟结果的有效性,证实了缩窄主动脉内部存在湍流区假设的有效性,也证实了LES湍流模型模拟心血管血流的有效性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Blood Flow Simulation in an Aorta with a mild coarctation Using Magnetic Resonance Angiography and Finite Volume Method
Coarctation of the aorta is one of the five main congenital cardiovascular failures, accounting for 6–8 percent of these failures. This research aimed to simulate the blood flow of a seventeen-year-old male teen with a mild coarctation at one-third of his aorta's descending branch. The simulation was performed by extracting the domain and the input pulsatile velocity signal as the boundary condition at the aorta entrance using magnetic resonance angiography (MRA) and the finite volume method (FVM), as well as a large eddy simulation (LES) turbulence model. The results were validated by comparing the blood flow static pressure from the numerical simulation to a clinical measurement available in the literature. The Inclusion of the turbulence model in the solution resulted in a static pressure for the heart’s normal function at the coarctation that agreed very well with the clinical measurement; the difference was just 0.39 mmHg. Therefore, the study confirmed the validity of the simulation results, the assumption that a turbulence regime exists inside an aorta with a coarctation, and the efficiency of the LES turbulence model for simulating cardiovascular flows.
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