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引用次数: 0
摘要
互惠易位是人类最常见的染色体结构异常。在这项研究中，细胞遗传学分析的结果进行了对夫妇的生殖史三流产和一个宫内死亡转介到我们的实验室。男性核型正常(46,XY)，易位46XX t (6;8) (q25-27;Q23)的测定。在大约4%的反复流产的夫妇中，父母中的一方是平衡易位或罗伯逊易位携带者。因此，反复流产的夫妇应建议进行细胞遗传学分析。关键词:反复流产，胎儿损耗，反向易位
RECIPROCAL TRANSLOCATION t (6; 8) (q25-27; q23): CASE REPORT
Reciprocal translocations are the most common structural chromosomal abnormalities in humans. In this study, the results of cytogenetic analysis performed on a couple with a reproductive history of three abortions and one intrauterine death referred to our laboratory are presented. Normal karyotype (46, XY) in male and reciprocal translocation 46XX t (6; 8) (q25-27; q23) in female were determined. In about 4% of couples with recurrent miscarriages, one of the parents is either a balanced reciprocal translocation or a robertsonian translocation carrier. Therefore, cytogenetic analysis should be recommended to couples with recurrent miscarriages.
Keywords: Recurrent Abortions, Fetal Wastage, Reciprocal Translocation
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