R. Kocián, C. Koehler, S. Bajsova, J. Jarkovský, I. Zapardiel, G. Martino, L. V. van Lonkhuijzen, B. Sehnal, O. A. Sánchez, Blanca Gil- Ibañez, F. Martinelli, Jiri Presl, L. Minář, R. Marek, P. Kascak, P. Havelka, M. Michal, T. Van Gorp, K. Němejcová, D. Cibula
{"title":"病理超声对宫颈癌前哨淋巴结活检的重要性,Sentix研究的最终结果(CEEGOG-CX01;ENGOT-CX2;NCT02494063)","authors":"R. Kocián, C. Koehler, S. Bajsova, J. Jarkovský, I. Zapardiel, G. Martino, L. V. van Lonkhuijzen, B. Sehnal, O. A. Sánchez, Blanca Gil- Ibañez, F. Martinelli, Jiri Presl, L. Minář, R. Marek, P. Kascak, P. Havelka, M. Michal, T. Van Gorp, K. Němejcová, D. Cibula","doi":"10.1136/ijgc-2022-esgo.69","DOIUrl":null,"url":null,"abstract":"2022-RA-908-ESGO Figure 1 Conclusion Pathological ultrastaging is a key component of the SLN concept in cervical cancer. It enables detection of additional 44% of patients with N1 (MAC, MIC) and almost all (91%) with ITC. The detection of positive SLN directly correlates with the intensity of ultrastaging. Four levels should become an international standard, which allows to detect over 90% of N1 (MAC, MIC). 2022-VA-920-ESGO ADRENAL GLAND RECURRENT CERVICAL CANCER TREATED BY MINIMALLY INVASIVE APPROACH Andrea Rosati, Camilla Certelli, Giulia Scaglione, Alessandro Baroni, Alex Federico, Filippo Maria Capomacchia, Pierfrancesco Greco, Francesco Fanfani, Giovanni Scambia, Valerio Gallotta. Policlinico Agostino Gemelli, Roma, Italy 10.1136/ijgc-2022-ESGO.70 Introduction/Background Recurrence of disease represents a clinical challenge in cervical cancer patients and the choice of the best treatment depends on previous therapy and site of recurrent tumor. The paraortic lymph nodes and the lungs were the extrapelvic areas more frequently involved, whereas adrenal gland involvement is rarely reported. Some reports confirmed the survival benefit of secondary radical surgery in confined recurrence, although this finding has been rarely investigated in the literature with only a few case series reported mostly focusing on lung metastases. Methodology Here a case of isolated adrenal gland cervical cancer recurrence in a 62-year-old woman is presented. Preoperative computed and emission tomography scans detected a nodule of 26 mm with increased uptake involving the medial lip of the right adrenal gland and a lymph node of 8 mm behind the inferior vena cava. A retrocaval lymphadenectomy and right adrenalectomy was performed. In this video we showed a minimally invasive approach tailored on the patient disease with the help of intraoperative ultrasound. Results We reached a residual tumor of zero with good operation times. No intra or postoperative complications occurred. Final histology confirmed the metastatic involvement of both the adrenal gland and the retrocaval lymph node by an undifferentiated carcinoma. After a multidisciplinary board evaluation, the patient underwent chemotherapy. Conclusion Minimally invasive surgery in selected patients with isolated extrapelvic cervical cancer recurrence is feasible and safe. Since radicality may be guaranteed by intraoperative imaging such as ultrasound, surgery can be tailored on the single patient and disease. 2022-RA-926-ESGO AWARENESS, ATTITUDES AND PRACTICES OF WOMEN IN RELATION TO CERVICAL CANCER SCREENING IN MAINLAND CHINA Sumeng Wang, Youlin Qiao. Department of Cancer Epidemiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; Center for Global Health, School of Population Medicine and Public Health, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China 10.1136/ijgc-2022-ESGO.7","PeriodicalId":114847,"journal":{"name":"Cervical cancer","volume":"83 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"2022-RA-908-ESGO The importance of pathological ultrastaging for sentinel lymph nodebiopsy in cervical cancer, the final outcome of the Sentix study (CEEGOG-CX01; ENGOT-CX2; NCT02494063)\",\"authors\":\"R. Kocián, C. Koehler, S. Bajsova, J. Jarkovský, I. Zapardiel, G. Martino, L. V. van Lonkhuijzen, B. Sehnal, O. A. Sánchez, Blanca Gil- Ibañez, F. Martinelli, Jiri Presl, L. Minář, R. Marek, P. Kascak, P. Havelka, M. Michal, T. Van Gorp, K. Němejcová, D. Cibula\",\"doi\":\"10.1136/ijgc-2022-esgo.69\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"2022-RA-908-ESGO Figure 1 Conclusion Pathological ultrastaging is a key component of the SLN concept in cervical cancer. It enables detection of additional 44% of patients with N1 (MAC, MIC) and almost all (91%) with ITC. The detection of positive SLN directly correlates with the intensity of ultrastaging. Four levels should become an international standard, which allows to detect over 90% of N1 (MAC, MIC). 2022-VA-920-ESGO ADRENAL GLAND RECURRENT CERVICAL CANCER TREATED BY MINIMALLY INVASIVE APPROACH Andrea Rosati, Camilla Certelli, Giulia Scaglione, Alessandro Baroni, Alex Federico, Filippo Maria Capomacchia, Pierfrancesco Greco, Francesco Fanfani, Giovanni Scambia, Valerio Gallotta. Policlinico Agostino Gemelli, Roma, Italy 10.1136/ijgc-2022-ESGO.70 Introduction/Background Recurrence of disease represents a clinical challenge in cervical cancer patients and the choice of the best treatment depends on previous therapy and site of recurrent tumor. The paraortic lymph nodes and the lungs were the extrapelvic areas more frequently involved, whereas adrenal gland involvement is rarely reported. Some reports confirmed the survival benefit of secondary radical surgery in confined recurrence, although this finding has been rarely investigated in the literature with only a few case series reported mostly focusing on lung metastases. Methodology Here a case of isolated adrenal gland cervical cancer recurrence in a 62-year-old woman is presented. Preoperative computed and emission tomography scans detected a nodule of 26 mm with increased uptake involving the medial lip of the right adrenal gland and a lymph node of 8 mm behind the inferior vena cava. A retrocaval lymphadenectomy and right adrenalectomy was performed. In this video we showed a minimally invasive approach tailored on the patient disease with the help of intraoperative ultrasound. Results We reached a residual tumor of zero with good operation times. No intra or postoperative complications occurred. Final histology confirmed the metastatic involvement of both the adrenal gland and the retrocaval lymph node by an undifferentiated carcinoma. After a multidisciplinary board evaluation, the patient underwent chemotherapy. Conclusion Minimally invasive surgery in selected patients with isolated extrapelvic cervical cancer recurrence is feasible and safe. Since radicality may be guaranteed by intraoperative imaging such as ultrasound, surgery can be tailored on the single patient and disease. 2022-RA-926-ESGO AWARENESS, ATTITUDES AND PRACTICES OF WOMEN IN RELATION TO CERVICAL CANCER SCREENING IN MAINLAND CHINA Sumeng Wang, Youlin Qiao. Department of Cancer Epidemiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; Center for Global Health, School of Population Medicine and Public Health, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China 10.1136/ijgc-2022-ESGO.7\",\"PeriodicalId\":114847,\"journal\":{\"name\":\"Cervical cancer\",\"volume\":\"83 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cervical cancer\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1136/ijgc-2022-esgo.69\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cervical cancer","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1136/ijgc-2022-esgo.69","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
摘要
结论病理性超转移是宫颈癌SLN概念的关键组成部分。它能够检测额外44%的N1 (MAC、MIC)患者和几乎所有(91%)ITC患者。SLN阳性的检测与超载强度直接相关。4级应成为国际标准,允许检测90%以上的N1 (MAC, MIC)。Andrea Rosati, Camilla Certelli, Giulia Scaglione, Alessandro Baroni, Alex Federico, Filippo Maria Capomacchia, Pierfrancesco Greco, Francesco Fanfani, Giovanni Scambia, Valerio Gallotta。意大利,罗马,10.1136/ijgc-2022-ESGO.70介绍/背景疾病复发是宫颈癌患者的临床挑战,选择最佳治疗取决于既往治疗和肿瘤复发部位。腹主动脉旁淋巴结和肺是盆腔外区域更常受累,而肾上腺受累很少报道。一些报道证实了继发性根治性手术对局限性复发患者的生存益处,尽管这一发现在文献中很少被研究,只有少数病例系列报道主要集中在肺转移。本文报告一例孤立性肾上腺宫颈癌复发的62岁妇女。术前计算机和放射断层扫描发现一个26毫米的结节,摄取增加,累及右肾上腺内侧唇和下腔静脉后方8毫米的淋巴结。行腔后淋巴结切除术和右肾上腺切除术。在这个视频中,我们展示了在术中超声的帮助下,针对患者疾病量身定制的微创方法。结果手术时间长,肿瘤残余为零。无术中及术后并发症发生。最终组织学证实肾上腺和腔静脉后淋巴结转移累及为未分化癌。在多学科委员会评估后,患者接受了化疗。结论微创手术治疗孤立性盆腔外宫颈癌复发是可行、安全的。由于术中成像(如超声)可以保证根治性,因此可以针对单个患者和疾病量身定制手术。王苏萌,乔友林。中国大陆妇女对宫颈癌筛查的认知、态度和实践。中国医学科学院、北京协和医学院肿瘤医院国家肿瘤中心/国家肿瘤临床研究中心肿瘤流行病学研究室;7 .中国医学科学院、北京协和医学院人口医学与公共卫生学院全球健康研究中心,北京10.1136/ijgc-2022- esgo . 6
2022-RA-908-ESGO The importance of pathological ultrastaging for sentinel lymph nodebiopsy in cervical cancer, the final outcome of the Sentix study (CEEGOG-CX01; ENGOT-CX2; NCT02494063)
2022-RA-908-ESGO Figure 1 Conclusion Pathological ultrastaging is a key component of the SLN concept in cervical cancer. It enables detection of additional 44% of patients with N1 (MAC, MIC) and almost all (91%) with ITC. The detection of positive SLN directly correlates with the intensity of ultrastaging. Four levels should become an international standard, which allows to detect over 90% of N1 (MAC, MIC). 2022-VA-920-ESGO ADRENAL GLAND RECURRENT CERVICAL CANCER TREATED BY MINIMALLY INVASIVE APPROACH Andrea Rosati, Camilla Certelli, Giulia Scaglione, Alessandro Baroni, Alex Federico, Filippo Maria Capomacchia, Pierfrancesco Greco, Francesco Fanfani, Giovanni Scambia, Valerio Gallotta. Policlinico Agostino Gemelli, Roma, Italy 10.1136/ijgc-2022-ESGO.70 Introduction/Background Recurrence of disease represents a clinical challenge in cervical cancer patients and the choice of the best treatment depends on previous therapy and site of recurrent tumor. The paraortic lymph nodes and the lungs were the extrapelvic areas more frequently involved, whereas adrenal gland involvement is rarely reported. Some reports confirmed the survival benefit of secondary radical surgery in confined recurrence, although this finding has been rarely investigated in the literature with only a few case series reported mostly focusing on lung metastases. Methodology Here a case of isolated adrenal gland cervical cancer recurrence in a 62-year-old woman is presented. Preoperative computed and emission tomography scans detected a nodule of 26 mm with increased uptake involving the medial lip of the right adrenal gland and a lymph node of 8 mm behind the inferior vena cava. A retrocaval lymphadenectomy and right adrenalectomy was performed. In this video we showed a minimally invasive approach tailored on the patient disease with the help of intraoperative ultrasound. Results We reached a residual tumor of zero with good operation times. No intra or postoperative complications occurred. Final histology confirmed the metastatic involvement of both the adrenal gland and the retrocaval lymph node by an undifferentiated carcinoma. After a multidisciplinary board evaluation, the patient underwent chemotherapy. Conclusion Minimally invasive surgery in selected patients with isolated extrapelvic cervical cancer recurrence is feasible and safe. Since radicality may be guaranteed by intraoperative imaging such as ultrasound, surgery can be tailored on the single patient and disease. 2022-RA-926-ESGO AWARENESS, ATTITUDES AND PRACTICES OF WOMEN IN RELATION TO CERVICAL CANCER SCREENING IN MAINLAND CHINA Sumeng Wang, Youlin Qiao. Department of Cancer Epidemiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; Center for Global Health, School of Population Medicine and Public Health, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China 10.1136/ijgc-2022-ESGO.7