循环室尺寸对商用干粉吸入器气溶胶输送效率的影响

2017 IEEE 17th International Conference on Bioinformatics and Bioengineering (BIBE) Pub Date : 2017-10-01 DOI:10.1109/BIBE.2017.00011

Tijana Tuteric, Aleksandra Vulovic, S. Cvijić, S. Ibrić, N. Filipovic

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引用次数: 3

摘要

本研究的目的是分析循环室尺寸的变化如何影响干粉吸入器(DPI)雾化器®中的气溶胶颗粒沉积。将模拟流体流动(空气)的计算流体力学(CFD)与模拟颗粒流动的离散相模型(DPM)相结合，可以更好地了解吸入器气流场中颗粒的分散情况。模拟输入20mg气溶胶粒子，初始速度为11,79166m/s。尺寸变化影响最大速度，以及沉积颗粒的百分比。根据这些信息，我们能够计算出出口的颗粒数量，并比较当循环室高度增加时效率的降低。通过这种方式获得的知识有助于设备性能优化。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Effect of Circulation Chamber Dimensions on Aerosol Delivery Efficiency of a Commercial Dry Powder Inhaler Aerolizer®

Aim of this study was to analyze how modifications in circulation chamber dimensions affect aerosol particle deposition in a Dry Powder Inhaler (DPI) Aerolizer®. Combining computational fluid dynamics (CFD), for simulation of fluid flow (air), with discrete phase model (DPM) for particles simulation, we can better understand particle dispersion within inhalers air flow field. Input in the simulation was 20mg of aerosol particles with initial velocity of 11,79166m/s. Dimension change influences maximum velocities, as well as percentage of deposited particles. Based on these information we were able to calculate the number of particles on the outlet and compare efficiency reduction when circulation chamber height increased. Knowledge obtained in this way can help in device performance optimization.

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2017 IEEE 17th International Conference on Bioinformatics and Bioengineering (BIBE)

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