具有媒体报道、垂直传播和时间延迟的艾滋病毒/艾滋病流行模型

T. Teng, E. D. Lara-Tuprio, J. M. Macalalag
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引用次数: 5

摘要

在本文中,我们提出并研究了人类免疫缺陷病毒(HIV)传播的时滞室室模型,这种疾病可能导致感染的晚期阶段,称为获得性免疫缺陷综合征(AIDS),在性活跃人群中存在媒体报道。还考虑将垂直传播纳入受感染个体的招募中。此外,模型中还加入了两个时滞。一个延迟τ1涵盖从收集社区感染总数的统计数据到通过媒体向公众报告这些信息的这段时间。另一个延迟τ2对应于受感染的新生儿达到性成熟年龄的时间。若阈值R0 < 1,则唯一平衡点为全局渐近稳定的无病平衡点。如果阈值R0和R00均大于1,则存在唯一的地方性均衡,当不考虑媒体覆盖时,该均衡全局渐近稳定。当不存在垂直传输但考虑媒体覆盖时,系统在媒体延迟的某个临界值处发生Hopf分岔。通过数值模拟来说明理论结果。在本文中,我们提出并研究了人类免疫缺陷病毒(HIV)传播的时滞室室模型,这种疾病可能导致感染的晚期阶段,称为获得性免疫缺陷综合征(AIDS),在性活跃人群中存在媒体报道。还考虑将垂直传播纳入受感染个体的招募中。此外,模型中还加入了两个时滞。一个延迟τ1涵盖从收集社区感染总数的统计数据到通过媒体向公众报告这些信息的这段时间。另一个延迟τ2对应于受感染的新生儿达到性成熟年龄的时间。若阈值R0 < 1,则唯一平衡点为全局渐近稳定的无病平衡点。如果阈值R0和R00均大于1,则存在唯一的地方性均衡,该均衡…
本文章由计算机程序翻译,如有差异,请以英文原文为准。
An HIV/AIDS epidemic model with media coverage, vertical transmission and time delays
In this paper, we propose and study a time-delay compartmental model for human immunodeficiency virus (HIV) transmission, a disease which may lead to an advanced stage of infection called acquired immunodeficiency syndrome (AIDS), in a sexually active population with the presence of media coverage. The inclusion of vertical transmission in the recruitment of infected individuals is also considered. Moreover, two time delays are incorporated in the model. One delay τ1 covers the period from the time of gathering statistical data on the total number of infections in the community up to the time that these information are reported to the public through media. The other delay τ2 corresponds to the period that an infected newborn baby reaches the age of sexual maturity. If the threshold value R0 < 1, then the only equilibrium point is the disease-free equilibrium which is globally asymptotically stable. If the threshold values R0 and R00 are both greater than 1, then a unique endemic equilibrium exists, which is globally asymptotically stable when media coverage is not considered. When there is no vertical transmission but media coverage is considered, the system undergoes a Hopf bifurcation at some critical value of the media delay. Numerical simulations are presented to illustrate theoretical results.In this paper, we propose and study a time-delay compartmental model for human immunodeficiency virus (HIV) transmission, a disease which may lead to an advanced stage of infection called acquired immunodeficiency syndrome (AIDS), in a sexually active population with the presence of media coverage. The inclusion of vertical transmission in the recruitment of infected individuals is also considered. Moreover, two time delays are incorporated in the model. One delay τ1 covers the period from the time of gathering statistical data on the total number of infections in the community up to the time that these information are reported to the public through media. The other delay τ2 corresponds to the period that an infected newborn baby reaches the age of sexual maturity. If the threshold value R0 < 1, then the only equilibrium point is the disease-free equilibrium which is globally asymptotically stable. If the threshold values R0 and R00 are both greater than 1, then a unique endemic equilibrium exists, which ...
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