用双头PMT ClearPET/spl交易/原型验证GEANT3模拟研究

K. Ziemons, U. Heinrichs, M. Streun, U. Pietrzyk
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引用次数: 0

摘要

ClearPET/spl贸易/项目是由水晶透明合作组织(CCC)的工作组提出的,旨在开发一种2/sup / generation高性能小动物正电子发射断层扫描仪(PET)。通过使用混合镥钇铝钙钛矿(LuYAP:Ce)和氧化硅酸镥(LSO)闪烁晶体的光交换排列,预计ClearPET/spl贸易/相机将具有高灵敏度和高空间分辨率。利用在GEANT3 (CERN, Geneva, Switzerland)上实现的蒙特卡罗模拟包,对基于光电倍增管(PMT)的ClearPET相机进行了设计优化。已经建立了一个双头原型来测试前端电子器件,并用于验证GEANT3仿真工具的实现。根据实验方案进行了多次模拟,测量了轴向和径向的固有分辨率和灵敏度分布。包括约27.0%的平均能量分辨率,模拟的固有分辨率约为(1.41/spl plusmn/0.11)mm,而测量的分辨率为(1.48/spl plusmn/0.06)mm。模拟灵敏度曲线轴向和径向的均方差分别为12.6%和3.6%。令人满意的是,这些结果对所有设计都具有代表性,并确认了扫描仪的几何形状。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Validation of GEANT3 simulation studies with a dual-head PMT ClearPET/spl trade/ prototype
The ClearPET/spl trade/ project is proposed by working groups of the Crystal Clear Collaboration (CCC) to develop a 2/sup nd/ generation high performance small animal positron emission tomograph (PET). High sensitivity and high spatial resolution is foreseen for the ClearPET/spl trade/ camera by using a phoswich arrangement combining mixed lutetium yttrium aluminum perovskite (LuYAP:Ce) and lutetium oxyorthosilicate (LSO) scintillating crystals. Design optimizations for the first photomultiplier tube (PMT) based ClearPET camera are done with a Monte-Carlo simulation package implemented on GEANT3 (CERN, Geneva, Switzerland). A dual-head prototype has been built to test the frontend electronics and was used to validate the implementation of the GEANT3 simulation tool. Multiple simulations were performed following the experimental protocols to measure the intrinsic resolution and the sensitivity profile in axial and radial direction. Including a mean energy resolution of about 27.0% the simulated intrinsic resolution is about (1.41/spl plusmn/0.11)mm compared to the measured of (1.48/spl plusmn/0.06)mm. The simulated sensitivity profiles show a mean square deviation of 12.6% in axial direction and 3.6% in radial direction. Satisfactorily these results are representative for all designs and confirm the scanner geometry.
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