骨、雌激素、力量训练研究转化为骨质疏松症预防研究与教育

L. Milliken, L. Houtkooper, L. Metcalfe, Vanessa A. Farrell, S. Going, T. Lohman
{"title":"骨、雌激素、力量训练研究转化为骨质疏松症预防研究与教育","authors":"L. Milliken, L. Houtkooper, L. Metcalfe, Vanessa A. Farrell, S. Going, T. Lohman","doi":"10.1249/TJX.0000000000000232","DOIUrl":null,"url":null,"abstract":"ABSTRACT Introduction/Purpose: Osteoporosis is a bone disease that a combination of exercise, hormone replacement therapy (HT), and calcium intake may help prevent by preserving or increasing bone mineral density (BMD) in postmenopausal women. The Bone, Estrogen, Strength Training (BEST) Study clinical trial was designed to determine the effects of exercise training on BMD in postmenopausal women either with or without HT. Methods: The BEST Study was unique because it included progressive resistance and weight-bearing exercises, addressed HT use, supplemented and documented calcium intake, provided robust intervention support, and extended the intervention protocol for multiple years. Results: The study findings demonstrated that postmenopausal women who had adequate calcium intake and followed the BEST exercise program maintained or increased their BMD. This article describes key lessons learned from the longitudinal BEST Study for translating the findings to the research community to improve future intervention research studies and to health professionals to inform osteoporosis prevention and bone health education. The BEST Study produced five lessons that can inform and improve osteoporosis prevention research and educational practice: 1) long-term bone health effects are important to study and require proactive strategies to obtain longitudinal funding support, 2) long-term retention of participants and compliance with study protocols require a participant focused study design and protocols, 3) extensive documentation of intervention protocols and sophisticated analytical strategies are essential to determine study intervention effects, 4) heterogeneity in responses to research study interventions should be expected and explored, and 5) osteoporosis prevention can be facilitated by translating the positive results from the BEST Study into practical educational tools. Conclusion: The BEST Study results can be translated into effective exercise and dietary practices to help prevent osteoporosis. Future research studies that use participant motivation and support protocols and meticulous documentation will further advance research in the prevention of osteoporosis.","PeriodicalId":315896,"journal":{"name":"Translational Journal of the ACSM","volume":"11 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Bone, Estrogen, Strength Training Study Translation to Osteoporosis Prevention Research and Education\",\"authors\":\"L. Milliken, L. Houtkooper, L. Metcalfe, Vanessa A. Farrell, S. Going, T. Lohman\",\"doi\":\"10.1249/TJX.0000000000000232\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"ABSTRACT Introduction/Purpose: Osteoporosis is a bone disease that a combination of exercise, hormone replacement therapy (HT), and calcium intake may help prevent by preserving or increasing bone mineral density (BMD) in postmenopausal women. The Bone, Estrogen, Strength Training (BEST) Study clinical trial was designed to determine the effects of exercise training on BMD in postmenopausal women either with or without HT. Methods: The BEST Study was unique because it included progressive resistance and weight-bearing exercises, addressed HT use, supplemented and documented calcium intake, provided robust intervention support, and extended the intervention protocol for multiple years. Results: The study findings demonstrated that postmenopausal women who had adequate calcium intake and followed the BEST exercise program maintained or increased their BMD. This article describes key lessons learned from the longitudinal BEST Study for translating the findings to the research community to improve future intervention research studies and to health professionals to inform osteoporosis prevention and bone health education. The BEST Study produced five lessons that can inform and improve osteoporosis prevention research and educational practice: 1) long-term bone health effects are important to study and require proactive strategies to obtain longitudinal funding support, 2) long-term retention of participants and compliance with study protocols require a participant focused study design and protocols, 3) extensive documentation of intervention protocols and sophisticated analytical strategies are essential to determine study intervention effects, 4) heterogeneity in responses to research study interventions should be expected and explored, and 5) osteoporosis prevention can be facilitated by translating the positive results from the BEST Study into practical educational tools. Conclusion: The BEST Study results can be translated into effective exercise and dietary practices to help prevent osteoporosis. Future research studies that use participant motivation and support protocols and meticulous documentation will further advance research in the prevention of osteoporosis.\",\"PeriodicalId\":315896,\"journal\":{\"name\":\"Translational Journal of the ACSM\",\"volume\":\"11 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-07-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Translational Journal of the ACSM\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1249/TJX.0000000000000232\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Translational Journal of the ACSM","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1249/TJX.0000000000000232","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

摘要:骨质疏松症是一种骨病,运动、激素替代疗法(HT)和钙摄入相结合可以通过保持或增加绝经后妇女的骨密度(BMD)来预防骨质疏松症。骨,雌激素,力量训练(BEST)研究临床试验旨在确定运动训练对绝经后妇女骨密度的影响,无论是否有激素治疗。方法:BEST研究的独特之处在于它包括渐进式阻力和负重运动,解决了HT的使用,补充并记录了钙的摄入,提供了强有力的干预支持,并延长了多年的干预方案。结果:研究结果表明,绝经后妇女如果摄入足够的钙并遵循BEST运动计划,可以维持或增加她们的骨密度。本文描述了从纵向BEST研究中获得的主要经验教训,以便将研究结果转化为研究社区,以改进未来的干预研究,并为卫生专业人员提供骨质疏松症预防和骨骼健康教育的信息。BEST研究提供了五个教训,可以为骨质疏松预防研究和教育实践提供信息和改进:1)长期的骨骼健康影响对研究很重要,需要积极主动的策略来获得纵向资金支持;2)长期保留参与者和遵守研究方案需要以参与者为中心的研究设计和方案;3)大量的干预方案文件和复杂的分析策略对于确定研究干预效果至关重要。4)对研究干预措施反应的异质性应予以预期和探索;5)通过将BEST研究的积极结果转化为实用的教育工具,可以促进骨质疏松症的预防。结论:BEST研究结果可以转化为有效的运动和饮食习惯,以帮助预防骨质疏松症。未来的研究使用参与者的动机和支持协议和细致的文件将进一步推进骨质疏松症的预防研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Bone, Estrogen, Strength Training Study Translation to Osteoporosis Prevention Research and Education
ABSTRACT Introduction/Purpose: Osteoporosis is a bone disease that a combination of exercise, hormone replacement therapy (HT), and calcium intake may help prevent by preserving or increasing bone mineral density (BMD) in postmenopausal women. The Bone, Estrogen, Strength Training (BEST) Study clinical trial was designed to determine the effects of exercise training on BMD in postmenopausal women either with or without HT. Methods: The BEST Study was unique because it included progressive resistance and weight-bearing exercises, addressed HT use, supplemented and documented calcium intake, provided robust intervention support, and extended the intervention protocol for multiple years. Results: The study findings demonstrated that postmenopausal women who had adequate calcium intake and followed the BEST exercise program maintained or increased their BMD. This article describes key lessons learned from the longitudinal BEST Study for translating the findings to the research community to improve future intervention research studies and to health professionals to inform osteoporosis prevention and bone health education. The BEST Study produced five lessons that can inform and improve osteoporosis prevention research and educational practice: 1) long-term bone health effects are important to study and require proactive strategies to obtain longitudinal funding support, 2) long-term retention of participants and compliance with study protocols require a participant focused study design and protocols, 3) extensive documentation of intervention protocols and sophisticated analytical strategies are essential to determine study intervention effects, 4) heterogeneity in responses to research study interventions should be expected and explored, and 5) osteoporosis prevention can be facilitated by translating the positive results from the BEST Study into practical educational tools. Conclusion: The BEST Study results can be translated into effective exercise and dietary practices to help prevent osteoporosis. Future research studies that use participant motivation and support protocols and meticulous documentation will further advance research in the prevention of osteoporosis.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信