The express-diagnostic of mammary diseases and forecasting the breast cancer development

The purpose of the present study is the development of methods for the express diagnosis of mammary diseases and for forecasting breast cancer development. This is based on the results of the estimation of autonomic nervous system condition, the immunity system and also intersystem interactions. The immune status and heart rate variability of each patient were examined. Immune status results included the following parameters: a T-system (CD-markers: CD3, CD4, CD8, CD 16, CD4/CD8), B-system: IgG, IgF6, IgA, monocytic phapocytosis (NST-test spontaneous, stimulus, phagocyte's reserve, reaction intensity), complement system and CIC. The heart rate variability was studied by 256 RR-intervals which were obtained in rest, during a tilt-test and during recovery. For the statistical characterisation of the heart rhythm the authors used Baevski's pressure index (IN), index of autonomic balance (IVR), autonomic parameter of the rhythm (VPR), parameter of adequacy of regulative process (PAPR). Summary parameters were determined of the relation of the basic parameters of variational pulsometry: mode (Mo), amplitude of the mode (AMo), variation scope (dX). The spectral analysis of the cardiorhythm was studied.