长波紫外线对镜片的影响。1 .用于体外检测和测量晶状体效应的模型系统。

Investigative ophthalmology Pub Date : 1976-05-01

J F Kuck

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引用次数: 0

摘要

用3-氨基三唑在长波紫外线下孵育大鼠、小鼠和鸡晶状体，发现亮氨酸的积累和掺入减少，谷胱甘肽的损失。当囊上皮池孵育时，对亮氨酸掺入的影响显著增强。该程序可以识别光敏剂或代谢抑制剂，当与紫外线一起作用时，它们会引起白内障。

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Effect of long-wave ultraviolet light on the lens. I. Model systems for detecting and measuring effect on the lens in vitro.

Rat mouse, and chick lenses incubated with 3-aminotriazole under long-wave ultraviolet (UV) show reduced accumulation and incorporation of leucine and a loss of glutathione. The effect on leucine incorporation is strikingly enhanced when capsule-epithelium pools are incubated. The procedure may identify photosensitizers or metabolic inhibitors which are cataractogenic when acting in conjunction with UV.

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Investigative ophthalmology

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