低成本微波针刺器用于肿瘤热消融治疗的可行性研究

Vincenza Portosi, A. Loconsole, M. Valori, V. Marrocco, F. Bonelli, G. Pascazio, Vito Lampignano, Antonella Fasano, R. Lorusso, F. Prudenzano
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引用次数: 3

摘要

微波应用器在医学上广泛应用于癌症治疗中的热消融/热疗。他们的目标是使受照射组织的局部温度适当升高,使肿瘤细胞消融或坏死。在这项工作中,研究了不同的优化方法后,设计和制造了一种用于热疗癌症治疗的低成本微创针敷器。应用器由一个同轴天线组成,工作在工业、科学和医疗(ISM)频段f=2.45 GHz。为了研究不同的几何形状、不同的3D打印材料、阻抗匹配技术和辐射截面,以适应14规(14g)和16规(16g)针的尺寸,进行了几次模拟和初步测量。此外,一个冷却系统被认为在较低的温度下维持周围的健康组织。一个原型已经构建和表征。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Feasibility investigation of low-cost microwave needle applicator for thermal ablation cancer therapy
Microwave (MW) applicators are widely used in medicine for thermal ablation / hyperthermia therapy in cancer treatment. Their goal is a proper local temperature increment of the irradiated tissue, allowing ablation or necrosis of tumoral cells. In this work, the design and fabrication of a low-cost mini-invasive needle applicator for hyperthermia cancer therapy is illustrated after the investigation of different optimization approaches. The applicator is composed by a coaxial antenna working in the Industrial, Scientific and Medical (ISM) frequency band at f=2.45 GHz. Several simulations and preliminary measurements are performed in order to investigate different geometries, different 3D printing materials, impedance matching techniques and radiating sections to fit 14 gauge (14 G) and 16 gauge (16 G) needle sizes. Moreover, a cooling system is considered to maintain the surrounding healthy tissue at lower temperature. A prototype has been constructed and characterized.
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