利用回渗法预测II型MODY3型糖尿病

Nawaz Khan, Chukwuemeka A. Ikejiaku, S. Rahman
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引用次数: 0

摘要

在这项研究中,基于神经网络的方法被用于预测是否存在成熟型糖尿病3型,即MODY3型糖尿病。本研究采用backpercolation神经网络算法预测导致MODY3型糖尿病的特定基因突变。为公共领域存储库中可用的遗传数据的数字表示分配了一组编码数值。在核苷酸的一部分中引入点突变用于突变预测以训练数据集。研究表明,backpercolation神经网络算法可用于训练和预测导致MODY3型糖尿病的基因点突变。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prediction of type II MODY3 diabetes using backpercolation
In this study, a neural network based approach is used to predict the presence of Maturity Onset Diabetes type 3, referred as MODY3 type II diabetes mellitus. The study has used backpercolation neural network algorithm to predict the specific genetic mutation that causes the MODY3 type II diabetes mellitus. A set of coded numeric values are assigned for numeric representation of genetic data that are available in public domain repositories. A point mutation is introduced in a portion of the nucleotide for the mutation prediction to train the data set. The study has demonstrated that backpercolation neural network algorithm is useful to train and to predict gene point mutation that leads to MODY3 type II diabetes.
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