蛋白质反应微流控芯片的快速成型

B. Wu, Chung-Kai Chen, G. Young, Yu-Ching Liu, Su-Jan Lee
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引用次数: 0

摘要

本文提出了一种微流控芯片原型设计的创新方法。通过设计模块化,单元模具批量制造和模具组装,聚合物微流控芯片的原型设计可以高效且具有成本效益。本文报道了一种用于蛋白质反应的微流控芯片的开发,包括结构制造和初始版本和改进版本的芯片测试。采用该方法,无需重新制作光刻掩模或重复昂贵的MEMS工艺,即可轻松实现设计修改。测试两个微流控芯片(5cm × 1cm和4cm × 3cm)的初步结果证明了所提出方法的可行性,并显示了在微流控芯片原型设计中节省时间和成本的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Fast Prototyping of Protein Reaction Microfluidic Chips
This paper presents an innovative approach for the prototyping of a microfluidic chip. By design modularization, unit mold batch fabrication, and mold assembly, the prototyping of polymeric microfluidic chips can be efficient and cost effective. The development of a microfluidic chip for protein reactions, including structure fabrication and chip testing for the initial and modified versions, is reported. Using the proposed approach, design modifications can be realized easily, without remaking photolithography masks or repeating the costly MEMS process. Initial results from testing two micro- fluidic chips (5cm by 1cm and 4cm by 3cm) prove the feasibility of the proposed method and show as well the potential for dramatic savings in time and cost in microfluidic chip prototyping.
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