一种用于神经探针针装置的无线供电显微光谱仪

Sang H. Choi, Min H. Kim, K. D. Song, H. Yoon, Uhn Lee
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引用次数: 2

摘要

神经系统异常的治疗,无论是侵入性的还是非侵入性的,都对设备的功能和尺寸提出了严格的要求。我们已经开发了一种微型光谱仪,用作植入式神经探针来监测突触中的神经化学。这种微型光谱仪基于美国宇航局发明的微型菲涅耳光栅,能够区分来自不同脑组织的发射光谱。微型光谱仪满足尺寸要求,并且能够探测神经化学和抑制电压通常与神经异常相关。这种神经探针针装置(PPD)配备了无线供电技术(WPT),无需植入电池即可连续工作。植入的神经PPD与神经电子接口和WPT一起,可以实时测量和控制/反馈神经异常的修复。我们将介绍用于监测大鼠大脑多巴胺的PPD/WPT联合装置的设计和性能,以展示目前的发展水平。该设备的未来工作将包括增加一个嵌入式专家系统,该系统能够通过常规的感知、处理和控制来执行神经功能的半自主管理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A wirelessly powered microspectrometer for neural probe-pin device
Treatment of neurological anomalies, whether done invasively or not, places stringent demands on device functionality and size. We have developed a micro-spectrometer for use as an implantable neural probe to monitor neuro-chemistry in synapses. The micro-spectrometer, based on a NASA-invented miniature Fresnel grating, is capable of differentiating the emission spectra from various brain tissues. The micro-spectrometer meets the size requirements, and is able to probe the neuro-chemistry and suppression voltage typically associated with a neural anomaly. This neural probe-pin device (PPD) is equipped with wireless power technology (WPT) to enable operation in a continuous manner without requiring an implanted battery. The implanted neural PPD, together with a neural electronics interface and WPT, enable real-time measurement and control/feedback for remediation of neural anomalies. The design and performance of the combined PPD/WPT device for monitoring dopamine in a rat brain will be presented to demonstrate the current level of development. Future work on this device will involve the addition of an embedded expert system capable of performing semi-autonomous management of neural functions through a routine of sensing, processing, and control.
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