稳定型冠心病(CAD)吸烟者慢性阻塞性肺疾病(COPD)患病率

A. Touil, F. Yangui, S. Antit, L. Zakhama, S. B. Youssef, M. Charfi
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引用次数: 0

摘要

慢性阻塞性肺病和CAD是常见的慢性疾病,具有共同的危险因素。慢性阻塞性肺病在很大程度上仍未得到充分诊断和治疗。我们的目的是描述使用CAD方法的突尼斯吸烟者的COPD患病率:在一项横断面研究中,招募了年龄超过35岁、因疑似CAD接受冠状动脉造影且报告吸烟≥10包年的患者。对所有参与者进行肺量测定,并根据GOLD标准定义COPD。≥50%的冠状动脉管腔狭窄证实了冠心病的存在。结果:122名男性进行了肺活量测定,平均年龄为59.3岁,平均生存年为52.3岁。平均CAD随访时间为3.9年。糖尿病、高血压和血脂异常是最常见的合并症。50%的患者发现有一个或多个危险的冠状动脉病变。45.9%的患者超声心动图正常。COPD患病率为19.7%。在24例COPD患者中,17例为新诊断。6例为轻度COPD,15例为中度COPD,2例为重度COPD,1例为极重度COPD。COPD患者平均FEV1为68.7%。copd相关症状为:慢性咳嗽(56%)、呼吸困难(76%)和喘息(28%)。36%的COPD患者存在肺动脉高压。慢性阻塞性肺病患者与非慢性阻塞性肺病患者的比较显示,慢性阻塞性肺病患者呼吸系统症状、胸片异常和肺动脉高压的发生率明显高于非慢性阻塞性肺病患者。结论:慢性阻塞性肺病在冠心病患者中患病率较高,多数患者虽有症状,但未得到充分诊断。有冠心病和呼吸道症状的吸烟者应评估气流限制
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevalence of chronic obstructive pulmonary disease (COPD) among smokers with stable coronary artery disease (CAD)
Introduction: COPD and CAD are common chronic diseases with shared risk factors. COPD continues to be largely underdiagnosed and undertreated. We aimed to describe the prevalence of COPD in Tunisian smokers with CAD Methods: In a cross-sectional study, patients over 35 years of age who underwent coronary angiography for suspected CAD and reported ≥10 pack-year of cigarette smoking were recruited. Spirometry was undertaken for all participants, and COPD was defined according to GOLD criteria. The finding of ≥50% coronary luminal narrowing confirmed the presence of CAD Results: Spirometry was undertaken for 122 men with mean age of 59.3 years and mean pack-year of 52.3. Mean CAD follow-up duration was 3.9 years. Diabetes, hypertension and dyslipidemia were the most common comorbidities. One or more threatening coronary lesions were found in 50% of patients. Echocardiography was normal in 45.9% of patients. The prevalence of COPD was 19.7%. Of the 24 patients with COPD,17 patients were newly diagnosed. Six patients had mild COPD,15 had moderate COPD,2 had severe COPD and 1 had very severe COPD. The mean FEV1 in COPD patients was 68.7%. COPD-related symptoms were:chronic cough(56%), dyspnea(76%) and wheezes(28%). Pulmonary arterial hypertension was observed in 36% of COPD patients. The comparison of patients with COPD with those without COPD showed that respiratory symptoms, chest-X-ray abnormality and pulmonary arterial hypertension were significantly more frequent in COPD patients Conclusion: There was a high prevalence of COPD among patients with CAD and most were underdiagnosed despite being symptomatic. Smokers with CAD and respi­ratory symptoms should be evaluated for airflow limitation
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