壳聚糖-羟基磷灰石复合材料骨科植入材料的实验研究与表征

Suchismita Chatterjee, A. Chanda, Kunal Pal
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摘要

本文主要研究了用干球磨法制备hap -壳聚糖复合材料,并对其物理、力学、微观结构和生物性能进行了详细的表征。密度和孔隙度分别为1700 ~ 2500 kg/m3和3 ~ 36%。同时测定了样品在s.b.f.暴露前后的硬度。对纳米HAp壳聚糖复合材料进行了体外生物矿化试验。用分析天平测量了复合材料表面磷灰石形成的重量增加量,并用扫描电镜观察了复合材料表面的形貌变化。制备的磷灰石通过x射线衍射表征。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Experimental study and characterization of Chitosan-HAP composite as orthopedic implant material
This study is focused on the preparation of HAp-chitosan composite using solid state mixing by dry ball milling method and detailed characterization of physical, mechanical, micro structural and biological properties. Density and porosity was obtained in the range of 1700-2500 kg/m3 and 3-36% respectively. Hardness was also measured before and after S.B.F exposure of the sample. In vitro bio mineralization test of nano HAp chitosan composite was carried out in S.B.F exposure. The amount of weight increase due to the formation of apatite on the composite surface was measured by analytical balance and morphology change on the surface was observed by scanning electron microscope (SEM). Characterization of produced apatite was achieved by x-ray diffraction.
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