{"title":"α硫辛酸联合皮质类固醇激素改善脊髓感染性疾病预后(附10例研究)","authors":"Xin Wang, A. Hubbard, G. Tan","doi":"10.15406/jnsk.2017.07.00255","DOIUrl":null,"url":null,"abstract":"Myelitis, Neuromylitis Optica (NMO) and Multiple Sclerosis (MS) are clinic common infectious diseases in spinal cord that are costly, progressive and often cause life-time disabilities. Methylprednisolone Sodium Succinate, a corticosteroid hormone, is a routine effective therapeutic drug for center nerve system (CNS) inflammation, especially applied for MS attacks [1]. However, long term and/or high dose use of corticosteroid hormone has serious side effects such as osteonecrosis of femoral head, cerebral hemorrhage, unstable blood pressure and blood sugar, disorder of kidney [2]. Therefore, corticosteroid hormone therapy is limited on clinical application.","PeriodicalId":106839,"journal":{"name":"Journal of Neurology and Stroke","volume":"142 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2017-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Alpha Lipoic Acid (Ala) Combining with Corticosteroid Hormone Improves the Outcome of Infectious Diseases in Spinal Cord (10 Cases Study)\",\"authors\":\"Xin Wang, A. Hubbard, G. Tan\",\"doi\":\"10.15406/jnsk.2017.07.00255\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Myelitis, Neuromylitis Optica (NMO) and Multiple Sclerosis (MS) are clinic common infectious diseases in spinal cord that are costly, progressive and often cause life-time disabilities. Methylprednisolone Sodium Succinate, a corticosteroid hormone, is a routine effective therapeutic drug for center nerve system (CNS) inflammation, especially applied for MS attacks [1]. However, long term and/or high dose use of corticosteroid hormone has serious side effects such as osteonecrosis of femoral head, cerebral hemorrhage, unstable blood pressure and blood sugar, disorder of kidney [2]. Therefore, corticosteroid hormone therapy is limited on clinical application.\",\"PeriodicalId\":106839,\"journal\":{\"name\":\"Journal of Neurology and Stroke\",\"volume\":\"142 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-10-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Neurology and Stroke\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15406/jnsk.2017.07.00255\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Neurology and Stroke","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15406/jnsk.2017.07.00255","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Alpha Lipoic Acid (Ala) Combining with Corticosteroid Hormone Improves the Outcome of Infectious Diseases in Spinal Cord (10 Cases Study)
Myelitis, Neuromylitis Optica (NMO) and Multiple Sclerosis (MS) are clinic common infectious diseases in spinal cord that are costly, progressive and often cause life-time disabilities. Methylprednisolone Sodium Succinate, a corticosteroid hormone, is a routine effective therapeutic drug for center nerve system (CNS) inflammation, especially applied for MS attacks [1]. However, long term and/or high dose use of corticosteroid hormone has serious side effects such as osteonecrosis of femoral head, cerebral hemorrhage, unstable blood pressure and blood sugar, disorder of kidney [2]. Therefore, corticosteroid hormone therapy is limited on clinical application.