维生素A和生物膜。Nota V -维生素A缺乏大鼠红细胞间质脂肪酸组成[作者译]。

L Carbini, E Dazzi, A Padalino
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引用次数: 0

摘要

两组白化雄性大鼠分别饲喂均衡和不含维生素a的饮食90天,观察红细胞膜脂肪酸组成的变化。用肝素分离血液,提取红细胞间质总脂,气相色谱法分析脂肪酸。人们注意到饱和脂肪酸的增加;与此同时,单不饱和脂肪酸,尤其是多不饱和脂肪酸减少;结果与不含维生素A的大鼠喂养30天和60天的结果一致,大鼠肝脏线粒体膜也发生了类似的变化,我们推测维生素A在一定程度上改变了不饱和脂肪酸的生物合成。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Vitamin "A" and biological membranes. Nota V - Fatty acid composition of erythrocyte stroma in vitamin A deficient rats (author's transl)].

Two groups of albino male rats, were fed for 90 days with a balanced and vitamin A-free diet rispectively, to observed changes, if any, in the fatty acid composition of erythrocyte membranes. The blood was separated with heparin, total lipids from erythocyte stroma were extracted and fatty acids analyzed by gaschromatography. It was noticed an increase in saturated fatty acids; at the same time mono- and, above all, polyunsaturated fatty acids decreased; the results agree with those obtained in rats fed for 30 and 60 days with Vitamin A-free diet as similar changes were observed in liver mitochondrial membranes of the rats, under study, we presume vitamin A modifies, to some extent, the biosyntesis of unsaturated fatty acids.

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