痴呆和虚弱

M. Watson, R. Campbell, Nandini Vallath, S. Ward, J. Wells
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摘要

本章概述了痴呆症的症状、流行病学、病因学和鉴别诊断,重点是晚期疾病。它讨论了痴呆症治疗的作用,晚期疾病面临的挑战,并指导识别和治疗常见症状,包括痴呆症和疼痛的行为和心理症状。本章还讨论了痴呆症状管理的药理学和非药理学方法,强调了姑息治疗的作用,当它是适当的转诊,和临终关怀。本章阐述了护理的一些有争议的方面。按照目前的速度,到2015年,英国将有85万人患有痴呆症,到2025年,这一数字预计将增加到100多万,到2051年将超过200万。这导致四分之一的人入院,据估计,痴呆症的健康和社会成本超过了中风、心脏病和癌症的总和。除了这些令人担忧的流行病学数据外,我们还需要考虑到家庭、护理人员和社会面临的巨大护理负担。终末期痴呆症往往落在专业化的缝隙之间,专业人员对终末期痴呆症管理策略的复杂性感到准备不足。由于多种原因,姑息治疗介入缓慢,但主要是因为痴呆症的发病轨迹比癌症慢得多,预后不明确。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Dementia and frailty
This chapter outlines the symptoms, epidemiology, aetiology, and differential diagnosis of dementia, with emphasis on advanced disease. It discusses the role of dementia treatments, the challenges faced with advanced disease, and guides to recognition and treatment of common symptoms, including behavioural and psychological symptoms of dementia and pain. The chapter also discusses pharmacological and non-pharmacological approaches to management of dementia symptoms, highlighting the role of palliative care, when it is appropriate to refer, and terminal care. The chapter illustrates some of the controversial aspects of care. At the current rate there will be 850,000 people with dementia in the UK by 2015, and this number is forecast to increase to over 1 million by 2025 and over 2 million by 2051.This is contributing to one in four hospital admissions, with the health and social costs of dementia estimated to be more than stroke, heart disease, and cancer combined. Along with these worrying progressive epidemiological figures, we need to take into account the immense caring burden for families, carers, and society. End-stage dementia often falls between the cracks of specialization, with professionals feeling under-prepared for the intricacies of end-stage dementia management strategies. Palliative care has been slow in its involvement for multiple reasons, but primarily because dementia has a much slower disease trajectory than cancer, with an unclear prognosis.
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