非糖尿病患者急性脑卒中患者糖尿病家族史与高血糖的相关性

M. S. A. Patwary, H. Ahasan, Md. Titu Miah, F. Munmun, A. Begum, Shamsuddoha Sarker Shanchay
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摘要

背景:血糖升高在卒中早期糖尿病患者中很常见。我们也知道,非糖尿病患者急性中风时血糖水平升高。目的:本研究的目的是评估糖尿病家族史与非糖尿病患者急性卒中期间新发糖尿病、空腹血糖受损、糖耐量受损的关系。方法:采用目的抽样的方法,在患者及其一级亲属中进行适当的糖尿病病史、文献资料和HbA1c水平低于6.5%(即为非糖尿病)的实验室支持,以确定患者。数据来自100名患者。采用问卷调查、早期预测、非糖尿病患者急性脑卒中时糖尿病家族史及血糖状况资料收集表等方法收集资料。该研究于2021年1月至2021年7月在达卡医学院医院医学部进行。结果:研究发现,患者平均年龄为61.76±7.33岁。48%的患者有糖尿病家族史(一级亲属)。52%的患者无糖尿病家族史。在对参与者的实验室调查分析中,HbA1c平均水平为5.69±0.65 mmol/L,在整个患者组中均为正常水平。检测患者空腹血糖(FBS),平均FBS为5.94±0.86。受访者中有48%有糖尿病家族史(一级亲属),其中8.3%血糖正常,66.7%为IGT, 25.0%为糖尿病。另一方面,52%的受访者没有糖尿病家族史,其中50%的人没有血糖异常,42.3%的人有IGT,只有7.7%的人患有糖尿病。结论:简而言之,研究发现,无糖尿病病史的急性中风患者可能出现中度血糖水平升高,而有糖尿病家族史的患者血糖水平明显升高。达卡医学院,2021;(1): 29日38-42
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Correlation of Family History of Diabetes Mellitus With Hyperglycaemia in Acute Stroke in Non Diabetic Patient
Background: Raised blood glucose is common in diabetic patients in early phase of stroke. It is also known that blood glucose level increases during acute stroke in non diabetic patients. Objective: Objective of this study was to assess the association between family history of diabetes and newly developed diabetes, impaired fasting glucose, impaired glucose tolerance during acute stroke in non diabetic patients. Methods: The purposive sampling method was applied to identify the patients by appropriate history taking about diabetes among the patients and their 1st degree relatives, documentary papers and laboratorial support evidenced by HbA1c level less than 6.5% (This means patient to be non diabetic). Data were collected from 100 patients. The data were collected by questionnaire, pre-tested earlier and data collection sheet illustrating the family history of diabetes mellitus and glycemic status during acute stroke among the nondiabetic patients. It was conducted from January, 2021 to July, 2021 in the Department of Medicine of Dhaka Medical College Hospital. Results: The study found that, mean age of the patents was 61.76±7.33 years. Family history of Diabetes Mellitus (first degree relative) was found among 48% patients.52% patients did not give family history of Diabetes Mellitus. During analysis of the lab investigations among the participants, mean HbA1c level was found 5.69± 0.65 mmol/L which was found normal among the entire patient group. Patients Fasting Blood Sugar (FBS) was tested and mean FBS level was 5.94±0.86.Among the respondents 48% gave family history(1st degree relative) of Diabetes of which 8.3% revealed normal glycemic status , 66.7% showed IGT and 25.0% were diabetic. On the other hand 52% respondents had no family history of Diabetes, among them 50% showed no glycemic abnormality, 42.3% showed IGT and only 7.7% were diabetic. Conclusion: In a nutshell, the study finds that, in patients with no history of diabetes who have acute stroke, may develop moderately elevated glucose levels and it is significantly higher in those who have family history of diabetes mellitus. J Dhaka Med Coll. 2021; 29(1): 38-42
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