一种新毒素对神经膜的作用机制。

Environmental letters Pub Date : 1975-01-01 DOI:10.1080/00139307509435852

T Narahashi, M S Brodwick, E J Schantz

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引用次数: 8

摘要

来自鞭毛虫的毒素通过选择性抑制细胞膜对钠离子渗透性增加的机制来阻断神经传导。这种作用只在神经膜外产生。这些作用与河豚毒素或蛤蚌毒素的作用完全相同。

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Mechanism of action of a new toxin from gonyaulax tamarensis on nerve membranes.

The toxin from the dinoflagellate Gonyaulax tamarensis blocks nervous conduction through a selective inhibition of the mechanism whereby the membrane undergoes an increase in permeability to sodium ions. The effect is exerted only from outside of the nerve membrane. These effects are exactly the same as those exerted by tetrodotoxin or saxitoxin.

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Environmental letters

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