用于生物制剂检测的多功能生物芯片

T. Vo‐Dinh, G. Griffin, A. Wintenberg, D. Stokes, D. Stratis, J. Mobley, R. Maples
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引用次数: 1

摘要

多功能生物芯片(MFB)是一种独特的系统,可以同时检测多种生物靶点。MFB是一种集成的多阵列生物芯片,它是通过将集成电路元件、电光激励/检测系统和生物受体探针结合到一个独立的集成微器件中而设计的。利用生物芯片作为抗体和DNA传感器,证明了MFB的多功能能力。研究表明,生物芯片技术为人类健康保护和国土防御提供了一种重要的病原体暴露预警工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Multi-functional biochip for biological agent detection
Multifunctional biochip (MFB) is a unique system that allows simultaneous detection of multiple biotargets simultaneously. The MFB is an integrated multi-array biochip, which is designed by combining integrated circuit elements, an electro-optics excitation/detection system, and bioreceptor probes into a self-contained and integrated microdevice. The multi-functional capability of MFB is demonstrated using the biochip as both an antibody-based and DNA sensor. The study indicates that the biochip technology provides an important tool to warn of exposure to pathogenic agents for use in human health protection and homeland defense.
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