[脑主要神经节苷的n -乙酰神经氨酸的代谢活性]。

Voprosy biokhimii mozga Pub Date : 1975-01-01

M I Prokhorova, M A Bespalova, A P Mukhina, S Iu Tumanova

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引用次数: 0

摘要

研究了2- 14c -乙酸酯注射后脑神经节苷类(GT1、GD1b、GD1a、GM1) n -乙酰神经氨酸的周转率。n -乙酰神经氨酸在GD1a和GM1中的比活性高于GD1b。氨基酸降低了n -乙酰神经氨酸的比活性，而水合氯提高了主要脑神经节苷的比活性。

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[Metabolic activity of the N-acetylneuraminic acid of the principle gangliosides of the brain].

The turnover rate of N-acetylneuraminic acid of brain gangliosides (GT1, GD1b, GD1a, GM1) was studied following the injection of 2-14C-acetate. The specific activity of N-acetylneuraminic acid in GD1a and GM1 was found to be higher than in GD1b. The administration of aminasine reduced the specific activity of N-acetylneuraminic acid whereas chlorhydrate increased that of major brain ganglosides.

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Voprosy biokhimii mozga

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