高级别CGIN患者子宫切除术后宫颈内膜腺癌的不寻常表现

T. Hall, A. Phillips, G. Schalkwyk, A. Bali
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引用次数: 0

摘要

宫颈癌是英国第14位最常见的癌症,每142名女性中就有1名被诊断出(1)。宫颈癌可以细分为许多组织学类型,其中宫颈内膜腺癌占所有癌症的20-25%(2)。随着宫颈鳞状癌前病变筛查的引入,宫颈癌鳞状细胞癌的数量减少,诊断为宫颈内膜腺癌的宫颈癌比例有所增加。宫颈内腺癌最常见的亚型与人乳头瘤病毒(HPV) 18型相关(3)。这些癌症通常具有弥漫性生长模式,并与原位腺癌(CGIN)密切相关,这使得疾病程度的测量变得困难。宫颈腺癌是根据(FIGO)国际妇产科联合会系统分期的。早期宫颈癌的治疗通常是增加手术切除的根治性,而晚期宫颈癌的治疗则是放疗和化疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Unusual presentation of Endocervical Adenocarcinoma following hysterectomy for high grade CGIN
Cervical carcinoma is the fourteenth most common cancer in the UK with 1 in every 142 women being diagnosed (1). Cervical carcinoma can be subdivided into numerous histological types, of which endocervical adenocarcinoma, represents 20-25% of all cancers (2). The proportion of cervical cancers diagnosed as endocervical adenocarcinomas has increased as the introduction of the cervical screening for squamous precancerous lesions has reduced the number of squamous cell cancers of the cervix. The most common subtype of endocervical adenocarcinoma is associated with human papillomavirus (HPV) type 18 (3). Often these cancers have a diffuse growth pattern and are closely associated with CGIN (adenocarcinoma in situ) making measurement of the extent of disease difficult. Cervical adenocarcinomas are staged according to the (FIGO) International Federation of Gynaecology and Obstetrics) system. Early stage cervical cancer is usually treated increasing radicality of surgical excision whilst advanced cervical cancer is treated with radiotherapy and chemotherapy.
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