疟疾计算机辅助诊断系统的优化

Y. Wibisono, A. Nugroho, M. Galinium
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引用次数: 0

摘要

疟疾是一种在热带国家发现的传染性热带疾病,由单细胞原生动物寄生虫引起。疟疾的显微镜诊断是通过人工检查从感染患者身上获得的薄血涂片来进行的。这种方法需要训练有素的人工交互,因此耗时且容易出错。疟疾计算机辅助诊断(CAD)的发展是为了加快诊断速度和保持诊断的准确性。实验结果表明,该系统能够识别被感染的红细胞、感染疟原虫的种类和生命阶段。但是,使用原始版本进行检测的平均运行时间为每张图像41.45秒,如果在现场使用,这就太长了。通过测量程序中每个进程的运行时间,可以通过重写或替换导致最长运行时间的算法来进行优化。提出了四种改进方法:带边界框的连通分量标记、不含内轮廓提取的轮廓跟踪标记、降尺度聚类分割和凹点聚类分割。实验结果表明,该系统在保持与原系统相同精度的情况下,平均运行时间为1.73秒。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Optimization on Malaria Computer Aided Diagnostic System
Malaria is infectious tropical disease found in tropical countries, caused by unicellular protozoan parasite. Microscopic based diagnosis of malaria is conducted by manually examining a thin blood smear that is acquired from the infected patients. This method requires a trained human interaction and therefore it is time consuming and prone to errors. Computer Aided Diagnostics (CAD) for Malaria was developed to speed up the diagnosis and maintaining the accuracy. The experimental results showed that the system is able to recognize the infected red blood cells, the species and the life phase of the infecting Plasmodium. However, the average runtime of the detection using the original version is 41.45 seconds per image, which is too long if it will be used in the field. By measuring the runtime of each process in the program, optimization can be done by re-writing or substituting the algorithm that causes the longest runtime. Four modifications are proposed: Connected Component Labelling with Bounding Box, Contour Tracing Labelling without Inner Contour Extraction, Downscaled Clump Splitting, and Concave Point Based Clump Splitting. The experimental results showed that the system has an average runtime of 1.73 seconds while maintaining the same level of accuracy compared to the original one.
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