Sofia Santos, P. Mascarenhas, S. Bandarra, A. C. Ribeiro, P. Maurício, I. Barahona
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引用次数: 1
摘要
在体外研究评估从牙胶粘剂释放的物质的细胞毒性潜力是缺乏的。本研究的目的是比较牙科胶粘剂Scotchbond Universal和Optibond Solo Plus提取物和一种处于实验阶段的胶粘剂的细胞毒性。将3T3小鼠成纤维细胞和MG-63人骨肉瘤成骨细胞样细胞暴露于连续提取物稀释液中24小时。采用MTT法测定细胞毒性。对于两种细胞系，未过滤的黏合剂提取物的细胞毒性顺序为T1(细胞毒性较小)< Optibond Solo Plus < Scotchbond Universal(细胞毒性最大)。
Evaluation of the Cytotoxic Potential of Adhesives, with Two on the Market: Scotchbond Universal and Optibond Solo Plus, and an Adhesive in the Experimental Phase: T1
In vitro studies evaluating the cytotoxic potential of substances released from dental adhesives are lacking. The purpose of this study was to compare the cytotoxicity of the extracts of dental adhesives Scotchbond Universal and Optibond Solo Plus, and an adhesive in the experimental phase: T1. 3T3 mouse fibroblast cells and MG-63 osteoblast-like cells from human osteosarcoma were exposed for 24 h to serial extract dilutions. Cytotoxicity was determined using an MTT assay. For both cell lines, the cytotoxicity order obtained, of the unfiltered adhesive extracts, was T1 (less cytotoxic) < Optibond Solo Plus < Scotchbond Universal (most cytotoxic).
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