{"title":"去甲基咪帕明的放射免疫测定。","authors":"S Spector, N L Spector, M P Almeida","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>This paper describes the production of antibodies against demethyl-imipramine (DMI). By using antisera, a radioimmunoassay was developed capable of detecting 0.2 ng of DMI which is linear up to 25 ng. The assay has been applied for the measurement of DMI in rat plasma and brain. The assay might find application especially when only limited amounts of blood, plasma or tissue are available.</p>","PeriodicalId":76387,"journal":{"name":"Psychopharmacology communications","volume":"1 4","pages":"421-9"},"PeriodicalIF":0.0000,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Radioimmunoassay for desmethylimipramine.\",\"authors\":\"S Spector, N L Spector, M P Almeida\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>This paper describes the production of antibodies against demethyl-imipramine (DMI). By using antisera, a radioimmunoassay was developed capable of detecting 0.2 ng of DMI which is linear up to 25 ng. The assay has been applied for the measurement of DMI in rat plasma and brain. The assay might find application especially when only limited amounts of blood, plasma or tissue are available.</p>\",\"PeriodicalId\":76387,\"journal\":{\"name\":\"Psychopharmacology communications\",\"volume\":\"1 4\",\"pages\":\"421-9\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1975-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Psychopharmacology communications\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Psychopharmacology communications","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
本文介绍了抗二甲基丙咪嗪(DMI)抗体的制备。通过使用抗血清，开发了一种能够检测0.2 ng DMI的放射免疫测定法，其线性到25 ng。该方法已应用于大鼠血浆和脑组织中DMI的测定。特别是当只有有限数量的血液、血浆或组织可用时，该分析可能会找到应用。
This paper describes the production of antibodies against demethyl-imipramine (DMI). By using antisera, a radioimmunoassay was developed capable of detecting 0.2 ng of DMI which is linear up to 25 ng. The assay has been applied for the measurement of DMI in rat plasma and brain. The assay might find application especially when only limited amounts of blood, plasma or tissue are available.
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