Opsoclonus with myoclonus.

A further case of opsoclonus with myoclonus is described. When this syndrome occurs in childhood an associated neuroblastoma should be excluded. In the majority of cases at all ages no underlying disease will be found, although a preceding history of minor upper respiratory or gastrointestinal infection may be elicited, suggesting that a possible encephalitis affecting brain stem mechanisms may be the cause. The prognosis is, as a rule, excellent although full recovery may not occur for many months. Corticosteroids and nitrazepam may have a place in the treatment of severely affected patients with distressing symptoms.