{"title":"单分子计数实验的蒙特卡罗模型","authors":"L. Davis, Li-Qiang Li","doi":"10.1364/laca.1994.thd.2","DOIUrl":null,"url":null,"abstract":"In experiments for fluorescence detection of single molecules in solution the background due to unrejected scattered light increases linearly with laser power while the dye molecule fluorescence signal and photodegradation probability saturate.","PeriodicalId":252738,"journal":{"name":"Laser Applications to Chemical Analysis","volume":"49 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Monte Carlo Model of a Single Molecule Counting Experiment\",\"authors\":\"L. Davis, Li-Qiang Li\",\"doi\":\"10.1364/laca.1994.thd.2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In experiments for fluorescence detection of single molecules in solution the background due to unrejected scattered light increases linearly with laser power while the dye molecule fluorescence signal and photodegradation probability saturate.\",\"PeriodicalId\":252738,\"journal\":{\"name\":\"Laser Applications to Chemical Analysis\",\"volume\":\"49 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1900-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Laser Applications to Chemical Analysis\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1364/laca.1994.thd.2\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Laser Applications to Chemical Analysis","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1364/laca.1994.thd.2","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Monte Carlo Model of a Single Molecule Counting Experiment
In experiments for fluorescence detection of single molecules in solution the background due to unrejected scattered light increases linearly with laser power while the dye molecule fluorescence signal and photodegradation probability saturate.