{"title":"运动员心血管疾病易感性分子遗传标记发生频率分析","authors":"A. S. Lyulchenko","doi":"10.46646/sakh-2021-2-58-62","DOIUrl":null,"url":null,"abstract":"For decades, cardiovascular diseases have been the leading cause of disability and death worldwide. Among athletes, the risk of cardiovascular disease increases significantly due to extreme physical exertion. Genotyping of the DNA samples of athletes and the control group based on the selected candidate genes for the pathology of the cardiovascular system was carried out. Carriers of unfavorable genotypes that significantly increase the risk of thrombosis were identified in the formed groups: dangerous mutations of blood clotting factors II and V were detected in 3.2 % of gymnasts and 17.1% of representatives of fire and rescue sports.","PeriodicalId":385455,"journal":{"name":"SAKHAROV READINGS 2021: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY Part 2","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2021-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"ANALYSIS OF THE FREQUENCY OF OCCURRENCE OF MOLECULAR GENETIC MARKERS OF PREDISPOSITION TO CARDIOVASCULAR PATHOLOGY IN ATHLETES\",\"authors\":\"A. S. Lyulchenko\",\"doi\":\"10.46646/sakh-2021-2-58-62\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"For decades, cardiovascular diseases have been the leading cause of disability and death worldwide. Among athletes, the risk of cardiovascular disease increases significantly due to extreme physical exertion. Genotyping of the DNA samples of athletes and the control group based on the selected candidate genes for the pathology of the cardiovascular system was carried out. Carriers of unfavorable genotypes that significantly increase the risk of thrombosis were identified in the formed groups: dangerous mutations of blood clotting factors II and V were detected in 3.2 % of gymnasts and 17.1% of representatives of fire and rescue sports.\",\"PeriodicalId\":385455,\"journal\":{\"name\":\"SAKHAROV READINGS 2021: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY Part 2\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-05-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"SAKHAROV READINGS 2021: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY Part 2\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.46646/sakh-2021-2-58-62\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"SAKHAROV READINGS 2021: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY Part 2","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.46646/sakh-2021-2-58-62","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
ANALYSIS OF THE FREQUENCY OF OCCURRENCE OF MOLECULAR GENETIC MARKERS OF PREDISPOSITION TO CARDIOVASCULAR PATHOLOGY IN ATHLETES
For decades, cardiovascular diseases have been the leading cause of disability and death worldwide. Among athletes, the risk of cardiovascular disease increases significantly due to extreme physical exertion. Genotyping of the DNA samples of athletes and the control group based on the selected candidate genes for the pathology of the cardiovascular system was carried out. Carriers of unfavorable genotypes that significantly increase the risk of thrombosis were identified in the formed groups: dangerous mutations of blood clotting factors II and V were detected in 3.2 % of gymnasts and 17.1% of representatives of fire and rescue sports.
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