子宫颈上皮细胞癌筛检

A. Qureshi, S. Rather, Pooja Bhagat
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引用次数: 2

摘要

宫颈恶性肿瘤是影响妇女的最常见的恶性肿瘤之一。它有很长的癌前阶段,为早期诊断和治疗提供了巨大的空间。虽然直接活检是诊断的金标准,而巴氏涂片染色是目前最有效的筛查方法,但这两种方法都需要昂贵的设备和专业知识。在这种规定有限的发展中国家,需要一种经济和更容易有效的替代办法。其中一种方法是用醋酸目视检查子宫颈(VIA试验)。研究设计:2006年6月至2007年5月,在斯利那加Lalla Ded政府医院进行了为期一年的前瞻性研究,其中1000名在妇科门诊就诊的已婚、性活跃妇女使用VIA作为筛查工具进行了宫颈疾病筛查。所有妇女进一步接受阴道镜检查,选定的病例进一步接受定向宫颈活检。结果在1000名接受筛查的女性中,170名(17%)检测出VIA阳性。其中大部分来自农村地区(87.6%),多段(3段及以上)占91.7%,社会经济阶层低(65.8%),平均年龄在20岁以下(62.9%)。在VIA阳性组中,经阴道镜进一步筛查的98名(58%)女性也有异常发现,72名(42%)女性没有阴道镜发现。阴道镜检查异常和VIA阳性的妇女通过定向活检进一步评估。在98名VIA和阴道镜阳性的女性中,有35名(36%)在定向活检中有异常的组织病理学发现。结论在资源有限的情况下,VIA可作为妇女宫颈癌筛查的一种较好的替代方法
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Screening For Cervical Carcinoma By VIA
IntroductionCervical malignancy is amongst the most common malignancies that affect women. It has a long precancerous stage providing tremendous scope for early diagnosis and treatment. Though directed biopsy is the gold standard for diagnosis, and Papinacolou staining (Pap Smear) is currently the most effective screening method, both require an expensive and expertise demanding setup. In developing countries where such provisions are limited, an economical and easier effective alternative is desirable. Onesuch method is visual inspection of cervix with acetic acid (VIA Test). Study designOne year prospective study was carried out at Government Lalla Ded hospital Srinagar from June 2006 to May 2007 in which 1000 married, sexually active women attending gynecology OPD were screened for cervical disease using VIA as the screening tool. All women were further subjected to colposcopy and selected cases further underwent directed cervical biopsy. ResultsAmong the 1000 women screened, 170(17%) tested VIA positive. Most of these were from rural areas (87.6%), multipara (para3 and above were 91.7%) and of low socio-economic class (65.8%) with average age less than 20 years in (62.9%). From the VIA positive group 98(58%) women on further screening by colposcopy had abnormal findings as well and 72(42%) had no colposcopic findings.Women with abnormal colposcopy and positive VIA results were further evaluated with directed biopsy. 35(36%) out of 98 VIA and colposcopy positive women had abnormal histopathology findings on directed biopsy. ConclusionIna resource limited setting,VIA can be used as a good alternative for screening women for cervical cancer
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