烧坏的睾丸肿瘤表现为宫颈和腹膜后淋巴结病

D. Das, S. Das Majumdar, S. Barik, Pritinanda Mishra, G. Parida, Anupama Muraleedharan, D. Parida, Mukund Sable, R. Patel, M. Shahin
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引用次数: 0

摘要

睾丸烧伤肿瘤是一种罕见的临床疾病。它通常不经任何治疗而自行消退,表现为腹膜后、纵隔、宫颈、肺和肝脏的转移。临床检查和睾丸的超声检查是关键,以提高怀疑诊断烧伤肿瘤。在这里,我们报告一个23岁的男性病例,他向我们提出了颈部左侧肿胀的投诉。颈部肿块活检提示转移性混合生殖细胞瘤,与卵黄囊瘤和胚胎癌一致。全身氟脱氧葡萄糖-正电子发射断层扫描-计算机断层扫描提示左颈部肿块和腹膜后淋巴结肿大。阴囊超声示右侧睾丸低回声不均匀,微钙化灶少。他接受了右上腹股沟睾丸切除术,没有发现肿瘤的证据。患者接受了四个周期的化疗,包括博来霉素、依托泊苷和以顺铂为基础的联合方案,对治疗有良好的反应。鉴于残存活菌和肿瘤标志物升高,患者接受了紫杉醇、异环磷酰胺和卡铂的二线化疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Burned-out testicular tumor presenting as cervical and retroperitoneal lymphadenopathy
A burned-out tumor of the testis is a rare clinical entity. It usually regresses spontaneously without any treatment and presents as metastasis to the retroperitoneum, mediastinum, cervical region, lungs, and liver. Clinical examination and ultrasound of the testis are pivotal to raising suspicion for the diagnosis of the burned-out tumor. Here, we report a case of a 23-year-old male who presented to us with a complaint of swelling on the left side of the neck. Biopsy from the neck mass suggested metastatic malignant mixed germ cell tumor, consistent with yolk sac tumor and embryonal carcinoma. The whole-body fluorodeoxyglucose-positron emission tomography-computed tomography suggested conglomerated left neck mass and retroperitoneal lymph node enlargement. Ultrasound of the scrotum suggested heterogeneously hypoechoic echotexture with few foci of microcalcification in the right testes. He underwent a right high inguinal orchidectomy, which showed no evidence of the tumor. The patient received four cycles of chemotherapy with bleomycin, etoposide, and a cisplatin-based combination regimen with a favorable response to the therapy. In view of residual viable disease and raised tumor markers, the patient received second-line chemotherapy with paclitaxel, ifosfamide, and carboplatin.
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