COVID-相关免疫性血小板减少症(COVID- itp)在大流行中的应用

M. Khan
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引用次数: 0

摘要

血小板计数<100 × 109/L,通常通过排除其他原因的方法诊断为血小板计数低已知环境(感染、药物、自身免疫等)或遗传易感性是ITP的危险因素。没有单一的检测方法可以识别ITP,但必须与患者的临床表现和相关检查相关联才能达到ITP的诊断。在过去的三个月里,我观察了大约60名患者,年龄在4到6岁之间,以男性为主,他们患有轻度到中度的血小板减少症。他们大多在常规检查中发现血小板计数低,很少有出血的表现。大多数患者有轻度虚弱和疲劳,但有发热症状。临床病史方面,部分患者在近6个月内感染新冠肺炎,但均有双剂疫苗接种史。头痛、视力模糊、胸痛、腹痛和腿痛是疫苗引起的血栓性血小板减少症(VITT)的常见临床表现经过仔细的临床检查,没有表面或内部出血的迹象,血栓形成的迹象,腿部水肿,蜂窝组织炎或四肢压痛。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
COVID- Associated Immune Thrombocytopenia (COVID-ITP) in Pandemic
platelet count <100 x 109/L, usually diagnosed by method of exclusion of other causes of low platelet count.1 Environmental (infection, medicine, autoimmunity etc.) or genetic predisposition are known risk factors for ITP. There is no single test that can identify ITP, but it is essential to correlate with clinical presentation of patient and relevant investigations to reach diagnosis of ITP. Over the last three months, I have observed about sixty patients of 4th to 6th decade age groups of male predominance who came with mild to moderate thrombocytopenia. Most of them were found to have low platelet count on routine checkup for other conditions and rarely did they have any bleeding manifestation. Majority of them had mild weakness and fatigue but were afebrile. On clinical history, some of them were suffered from COVID-19 infection within the last 6 months, but all had the history of double doses of COVID-19 vaccination. There were no association of headache, blurring of vision, chest pain, abdominal pain and leg pain which are common clinical findings of vaccine induced thrombotic thrombocytopenia (VITT).2 On careful clinical examination there were no signs of surface or internal bleeding, sign of thrombosis, leg edema, cellulitis or tenderness in the limbs.
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