{"title":"COVID-相关免疫性血小板减少症(COVID- itp)在大流行中的应用","authors":"M. Khan","doi":"10.37545/haematoljbd202178","DOIUrl":null,"url":null,"abstract":"platelet count <100 x 109/L, usually diagnosed by method of exclusion of other causes of low platelet count.1 Environmental (infection, medicine, autoimmunity etc.) or genetic predisposition are known risk factors for ITP. There is no single test that can identify ITP, but it is essential to correlate with clinical presentation of patient and relevant investigations to reach diagnosis of ITP. Over the last three months, I have observed about sixty patients of 4th to 6th decade age groups of male predominance who came with mild to moderate thrombocytopenia. Most of them were found to have low platelet count on routine checkup for other conditions and rarely did they have any bleeding manifestation. Majority of them had mild weakness and fatigue but were afebrile. On clinical history, some of them were suffered from COVID-19 infection within the last 6 months, but all had the history of double doses of COVID-19 vaccination. There were no association of headache, blurring of vision, chest pain, abdominal pain and leg pain which are common clinical findings of vaccine induced thrombotic thrombocytopenia (VITT).2 On careful clinical examination there were no signs of surface or internal bleeding, sign of thrombosis, leg edema, cellulitis or tenderness in the limbs.","PeriodicalId":137283,"journal":{"name":"Haematology Journal of Bangladesh","volume":"29 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2021-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"COVID- Associated Immune Thrombocytopenia (COVID-ITP) in Pandemic\",\"authors\":\"M. Khan\",\"doi\":\"10.37545/haematoljbd202178\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"platelet count <100 x 109/L, usually diagnosed by method of exclusion of other causes of low platelet count.1 Environmental (infection, medicine, autoimmunity etc.) or genetic predisposition are known risk factors for ITP. There is no single test that can identify ITP, but it is essential to correlate with clinical presentation of patient and relevant investigations to reach diagnosis of ITP. Over the last three months, I have observed about sixty patients of 4th to 6th decade age groups of male predominance who came with mild to moderate thrombocytopenia. Most of them were found to have low platelet count on routine checkup for other conditions and rarely did they have any bleeding manifestation. Majority of them had mild weakness and fatigue but were afebrile. On clinical history, some of them were suffered from COVID-19 infection within the last 6 months, but all had the history of double doses of COVID-19 vaccination. There were no association of headache, blurring of vision, chest pain, abdominal pain and leg pain which are common clinical findings of vaccine induced thrombotic thrombocytopenia (VITT).2 On careful clinical examination there were no signs of surface or internal bleeding, sign of thrombosis, leg edema, cellulitis or tenderness in the limbs.\",\"PeriodicalId\":137283,\"journal\":{\"name\":\"Haematology Journal of Bangladesh\",\"volume\":\"29 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-11-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Haematology Journal of Bangladesh\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.37545/haematoljbd202178\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Haematology Journal of Bangladesh","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.37545/haematoljbd202178","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
COVID- Associated Immune Thrombocytopenia (COVID-ITP) in Pandemic
platelet count <100 x 109/L, usually diagnosed by method of exclusion of other causes of low platelet count.1 Environmental (infection, medicine, autoimmunity etc.) or genetic predisposition are known risk factors for ITP. There is no single test that can identify ITP, but it is essential to correlate with clinical presentation of patient and relevant investigations to reach diagnosis of ITP. Over the last three months, I have observed about sixty patients of 4th to 6th decade age groups of male predominance who came with mild to moderate thrombocytopenia. Most of them were found to have low platelet count on routine checkup for other conditions and rarely did they have any bleeding manifestation. Majority of them had mild weakness and fatigue but were afebrile. On clinical history, some of them were suffered from COVID-19 infection within the last 6 months, but all had the history of double doses of COVID-19 vaccination. There were no association of headache, blurring of vision, chest pain, abdominal pain and leg pain which are common clinical findings of vaccine induced thrombotic thrombocytopenia (VITT).2 On careful clinical examination there were no signs of surface or internal bleeding, sign of thrombosis, leg edema, cellulitis or tenderness in the limbs.