减少HIV/AIDS传播的最优控制

P. D. Giamberardino, D. Iacoviello
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引用次数: 7

摘要

本文在最优控制理论的框架下研究了艾滋病病毒/艾滋病的传播控制问题。最近提出的一种模式已被采用;它考虑了两类易感对象,即明智的人和行为不谨慎的人,以及三类感染者,即尚未意识到自己的状况的人,艾滋病前期患者和艾滋病患者。控制行动包括通过宣传运动进行预防,减少不明智行为的受试者类别,通过检测运动进行预防,减少不知道感染病毒的受试者数量,并对诊断阳性的患者进行药物治疗。引入了一种旨在减少阳性诊断患者的成本指数,并提出了使用尽可能少的资源的冲突要求。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Optimal Control to reduce the HIV/AIDS spread
In this paper the problem of the HIV/AIDS spread reduction is addressed in the framework of optimal control theory. A model recently proposed has been adopted; it considers two classes of susceptible subjects, the wise people and the people with incautious behaviors, and three classes of infected, the ones still not aware of their status, the pre-AIDS patients and the AIDS ones. The control actions involve prevention by information campaign, to reduce the category of subjects with unwise behavior, by test campaign, to reduce the number of subjects not aware of having the virus, and medication on patients with a positive diagnosis. A cost index aiming at the reduction of patients with positive diagnosis is introduced with the conflicting requirements of using as less resources as possible.
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