Sara Farotto, C. Caltagirone, Giacomo Picci, V. Lippolis, R. Paolesse, C. di Natale', L. Lvova
{"title":"消炎药筛选的电位电子舌法","authors":"Sara Farotto, C. Caltagirone, Giacomo Picci, V. Lippolis, R. Paolesse, C. di Natale', L. Lvova","doi":"10.1109/ISOEN54820.2022.9789633","DOIUrl":null,"url":null,"abstract":"The development of potentiometric e-tongue system based on ion-selective electrodes prepared with PVC solvent polymeric membranes doped with new type of acyclic squaramide receptors L1-L5 for fast screening of non-steroidal anti-inflammatory drugs, ketoprofen and naproxen, in aqueous media is reported. The e-tongue system has shown the ability of effective discrimination among very similar ketoprofen (KF) and naproxen (NS) drugs, and the possibility to detect these analytes at the concentration as low as 0.7uM, with R2 of 0.947 and 0.919 NS-Na and KF-Lys, respectively, was shown.","PeriodicalId":427373,"journal":{"name":"2022 IEEE International Symposium on Olfaction and Electronic Nose (ISOEN)","volume":"12 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Potentiometric e-tongue for anti-inflammatory pharmaceuticals screening\",\"authors\":\"Sara Farotto, C. Caltagirone, Giacomo Picci, V. Lippolis, R. Paolesse, C. di Natale', L. Lvova\",\"doi\":\"10.1109/ISOEN54820.2022.9789633\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The development of potentiometric e-tongue system based on ion-selective electrodes prepared with PVC solvent polymeric membranes doped with new type of acyclic squaramide receptors L1-L5 for fast screening of non-steroidal anti-inflammatory drugs, ketoprofen and naproxen, in aqueous media is reported. The e-tongue system has shown the ability of effective discrimination among very similar ketoprofen (KF) and naproxen (NS) drugs, and the possibility to detect these analytes at the concentration as low as 0.7uM, with R2 of 0.947 and 0.919 NS-Na and KF-Lys, respectively, was shown.\",\"PeriodicalId\":427373,\"journal\":{\"name\":\"2022 IEEE International Symposium on Olfaction and Electronic Nose (ISOEN)\",\"volume\":\"12 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-05-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2022 IEEE International Symposium on Olfaction and Electronic Nose (ISOEN)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/ISOEN54820.2022.9789633\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2022 IEEE International Symposium on Olfaction and Electronic Nose (ISOEN)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/ISOEN54820.2022.9789633","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Potentiometric e-tongue for anti-inflammatory pharmaceuticals screening
The development of potentiometric e-tongue system based on ion-selective electrodes prepared with PVC solvent polymeric membranes doped with new type of acyclic squaramide receptors L1-L5 for fast screening of non-steroidal anti-inflammatory drugs, ketoprofen and naproxen, in aqueous media is reported. The e-tongue system has shown the ability of effective discrimination among very similar ketoprofen (KF) and naproxen (NS) drugs, and the possibility to detect these analytes at the concentration as low as 0.7uM, with R2 of 0.947 and 0.919 NS-Na and KF-Lys, respectively, was shown.
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