甲基纤维素、卡波姆和凡士林凝胶用于局部和透皮给药Zosyn(哌拉西林/他唑巴坦)抗生素的配方和比较表征

K. Yeboah, Ocimum Scientific Publishers Pty Ltd
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引用次数: 1

摘要

哌拉西林/他唑巴坦是一种广谱联合抗生素,用于治疗严重感染。它结合了哌拉西林的高抗生素活性和他唑巴坦的β-内酰胺酶抑制剂特性,有助于恢复细菌对抗生素的敏感性并防止耐药性。尽管有这种有趣的药理特征,但由于口服效果差,Zosyn只能静脉注射
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Formulation and Comparative Characterization of Methylcellulose, Carbomer and Petrolatum Gels for Topical and Transdermal Delivery of Zosyn (Piperacillin/Tazobactam) Antibiotics
Piperacillin/Tazobactam otherwise known as Zosyn is a broad-spectrum combination antibiotic used to treat severe infections. It combines the high antibiotic activity of piperacillin with β-lactamase inhibitor properties of tazobactam that helps to restore the susceptibility of bacteria to the antibiotic and prevents resistance. Despite this interesting pharmacological profile, Zosyn is given intravenously because of its poor oral
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