老年人群的大血管手术:心脏风险分层

Velimir Perić, M. Stosic, Dalibor Stojanović, Jelena Lilić, Nemanja Nikolić, Lela Lazović, Dimitrije Spasić, Stefan Stojanović, M. Lazarević
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引用次数: 0

摘要

对手术的依赖、手术技术的改进和围手术期管理导致老年人手术频率的急剧增加。根据欧洲心脏病学会和欧洲麻醉与重症监护学会的定义,考虑到心肌梗死和心脏骤停的频率,大血管手术被定义为高风险,高于5%。年龄是心肌梗死和心脏骤停的独立预测因子。心脏功能的改变是随着年龄增长而发生的主要变化。风险分层是一套程序,包括识别慢性全身性疾病,确定其严重程度、稳定性以及进一步评估和/或优化治疗的需要,目的是降低围手术期和术后死亡率和发病率。除了应用风险评分外,准确的风险分层还需要术前和术后生物标志物的联合应用。将生物标志物与评分系统相结合的主要思想是揭示那些具有临床未表现疾病的患者,这些患者具有死亡风险,但评分系统未检测到。生物标志物,如NT-proBNP和高度敏感的c反应蛋白,在老年血管手术中具有最大的预测作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Major vascular surgery in the geriatric population: Cardiac risk stratification
Reliance on surgery, improvements in surgical techniques, and perioperative management have led to a dramatic increase in the frequency of surgical procedures in the elderly population. According to the European Society of Cardiology and the European Society of Anaesthesiology and Intensive Care, major vascular surgery is defined as high-risk, considering the frequency of myocardial infarction and cardiac arrest, which is higher than 5%. Age is an independent predictor of myocardial infarction and cardiac arrest. Heart function alterations are primary changes that occur with advancing age. Risk stratification represents a set of procedures that include identifying chronic systemic diseases, determining their severity, stability and the need for further evaluation and/or therapy optimization, with the aim of reducing perioperative and postoperative mortality and morbidity. In addition to the application of risk scores, accurate risk stratification requires the combined application of both preoperative and postoperative biomarkers. The main idea of integrating biomarkers with scoring systems is to reveal those patients with clinically unmanifested disease, who carry a mortality risk and remain undetected by scoring systems. Biomarkers, such as NT-proBNP and highly sensitive C-reactive protein, have the greatest predictive influence in geriatric vascular surgery.
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