地理与人口之间:Covid-19的关键相互依赖关系和退出机制

Antonio Scala, Andrea Flori, A. Spelta, Emanuele Brugnoli, Matteo Cinelli, Walter Quattrociocchi, F. Pammolli
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引用次数: 7

摘要

我们开发了一个极简划分模型来分析2019冠状病毒病爆发期间意大利的流动限制政策。我们的研究结果表明,早期的封锁几乎不能及时改变疫情:此外,在封锁强度的临界值之外,一场似乎被完全平息的疫情在解除限制后会恢复。我们通过在模型中引入异构性来研究对锁定场景和退出机制的影响。特别是,我们将意大利地区视为独立的行政实体,其中通过不同年龄阶层进行社会互动。我们发现,由于流动性矩阵的稀疏性,一旦爆发开始,流行病在不同地区独立发展。此外,在流行病开始之后,与其他地区接触的影响很快就变得无关紧要。稀疏性解释了在不同区域观察到的延迟。类似的论点也适用于国际边界。我们还表明,忽视社会联系结构可能导致严重低估封城后的影响。然而,基于年龄等级的机制可以帮助用更温和的策略减轻反弹效应。最后,我们指出,通过描述关键参数对流行病非医疗缓解战略的影响,我们的结果可以推广到这个特定模型之外。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Between Geography and Demography: Key Interdependencies and Exit Mechanisms for Covid-19
We develop a minimalist compartmental model to analyze policies on mobility restriction in Italy during the Covid-19 outbreak. Our findings show that a early lockdowns barely shift the epidemic in time: moreover, beyond a critical value of the lockdown strength, an epidemic that seems to be quelled fully recovers after lifting the restrictions. We investigate the effects on lockdown scenarios and exit mechanisms by introducing heterogeneities in the model. In particular, we consider Italian regions as separate administrative entities in which social interactions through different age classes occur. We find that, due to the sparsity of the mobility matrix, epidemics developed independently in different regions once the outbreak starts. Moreover, after the epidemics ha started, the influence of contacts with other regions becomes soon irrelevant. Sparsity accounts for the observed delays across different regions. Analogous arguments would apply to the international borders. We also show how disregarding the structure of social contacts could lead to severe underestimation of the post-lockdown effects. Nevertheless, age class based mechanisms can help to mitigate rebound effects with milder strategies. Finally, we point out that our results can be generalized beyond this particular model by providing a description of the effects of key parameters on non-medical mitigation strategies for epidemics.
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