虚拟和办公室保守护理对肌肉骨骼疾病的相对疗效:倾向评分匹配比较研究(预印本)

H. Elliott, E. S. Moll, E. Olmsted
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摘要

倾向评分匹配是一种统计技术,它允许观察性研究控制研究组和对照组的差异,而没有建立长期随机试验的困难。这种方法非常适合不断发展的远程医疗领域,因为它的发展速度很快,而且它的普及相对较晚,对数据有限制。这些限制阻碍了随机对照试验应用于大多数问题,为使用倾向得分匹配创造了强有力的案例。目的在控制可能影响治疗方案选择的不同患者情况的情况下,评价单个诊所数字和面对面物理治疗的相对疗效。方法采用倾向评分匹配的方法,构建了890例患者的队列,平均分为数字患者和现场患者。我们根据损伤部位、损伤情况(第一次、第二次、第三次等)、报告的疼痛程度、年龄、是否有治疗尝试、性别和BMI(仅针对负重损伤部位)对患者进行匹配。我们评估了上半身组和下半身组的匹配队列在患者报告的疼痛改善、就诊完成、避免手术和患者报告的损伤解决方面的差异。结果我们采用双单侧t检验对数据进行分析。我们发现上半身数码患者在所有指标上的表现相当于0.5个标准差以内或优于面对面患者(所有指标p < 0.05)。下半身数字和面对面患者在访问完成、避免手术和报告损伤解决方面的表现在0.5个标准差内。(p < 0.05)。疼痛改善的结果尚无定论,95%的置信范围表明,数字患者可能表现相同(p = 0.48)或表现较差(p = 0.52)。结论:该数据表明远程治疗上肢损伤具有同等或更好的性能,数据表明,提高就诊完成率可以改善其他指标,而数字治疗的任何缺点都不能减少这些指标。由于患者经历的疼痛减轻程度各不相同,关于下体损伤的数据尚无定论。根据下半身患者的其他数据,这表明进一步的研究可能能够评估哪些下半身损伤可以通过远程物理治疗成功治疗,哪些不能。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Relative Efficacy of Virtual and In-Office Conservative Care for Musculoskeletal Conditions: A Propensity Score Matching Comparison Study (Preprint)
BACKGROUND Propensity Score Matching is a statistical technique which allows an observational study to control for differences in the study and comparison group, without the difficulty of establishing a long-term randomized trial. This method is very appropriate to the evolving field of telemedicine, due to the fast pace at which it is proceeding and the limitations on data imposed by its relatively recent popularization. These limitations prevent a randomized controlled trial from being applied to most questions, creating a strong case for the use of Propensity Score Matching. OBJECTIVE To evaluate the relative efficacy of digital and in-person physical therapy in a single clinic while controlling for the different patient circumstances that may affect the choice of treatment option. METHODS We used propensity score matching to construct a cohort of 890 patients split evenly between digital and onsite patients. We matched patients on injury location, instance of injury (first, second, third, etc.), reported pain level on presentation, age, presence or absence of prior treatment attempts, gender, and BMI (for weight-bearing injury locations only). We evaluated the matched cohorts in upper and lower body groups for differences in patient reported pain improvement, visit completion, avoidance of surgeries, and patient reported injury resolution. RESULTS We analyzed that data using a two-one-sided T-test. We found that upper body digital patients perform equivalent to within 0.5 standard deviations or superior to in-person patients on all metrics (p < 0.05 for all metrics). Lower body digital and in-person patients performed within 0.5 standard deviations on visit completion, avoidance of surgeries, and reported injury resolution. (p <0.05.) Results for pain improvement were inconclusive, with the 95% confidence range indicating a possibility of either equivalent performance (p = 0.48) or inferior performance for digital patients (p = 0.52). CONCLUSIONS The date indicates an equivalent or superior performance for remote treatment of upper body injuries, with data suggesting improved visit completion improves other metrics more than any disadvantages of digital treatment can reduce them. Data regarding lower body injuries is inconclusive, due to high varied level of pain reduction experienced by patients. In light of other data on lower body patients, this suggests that further research may be able to assess which lower body injuries can and cannot be successfully treated via remote physical therapy.
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