脑膜中动脉栓塞治疗慢性硬膜下血肿1例报告及文献复习

S. Paramasivam, Harihara Sudan
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引用次数: 1

摘要

慢性硬膜下血肿(cSDH)是一种常见的颅神经外科疾病,发病率和死亡率在2%至5%之间。常规治疗包括保守和手术抽吸。微创脑膜中动脉(MMA)栓塞正在成为一种潜在的治疗选择。我们报告我们的病例成功地管理MMA栓塞和回顾文献。cSDH的发生和发展与创伤性出血后的慢性炎症和血管生成周期有关。由于生长因子的作用,刺激引发的血管生成导致渗漏血管的生长,引起微出血,由于生理吸收能力超过了收集速度,导致硬膜下血管逐渐扩大。cSDH的管理战略旨在中断其发展的恶性循环,并向出血再吸收倾斜平衡。保守管理、药物治疗和手术治疗是常规治疗选择,手术后送被认为是金标准选择。然而,挑战包括抗血小板和抗凝血药物的复发和逆转及其相关的缺血性并发症风险。cSDH是脑膜向硬脑膜输送血液的一种病理,引起微出血,因此谨慎的做法是封闭血管,使平衡向吸收倾斜。MMA栓塞作为一种治疗选择已被大量发表的数据所使用。它可以作为一种独立的治疗方法用于症状最小的患者。聚乙烯醇和液体栓塞剂的技术成功率都很高。复发率一直很低,尽管重要的患者有抗血小板和抗凝剂在船上。它消除了因停止使用抗血小板和抗凝剂而引起的缺血性并发症。MMA栓塞也被认为是复发风险高的手术引流cSDH的辅助手段。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Middle meningeal artery embolization in the management of chronic subdural haematoma: A case report and review of literature
Chronic subdural hematoma (cSDH) is a common cranial neurosurgical condition with morbidity and mortality ranging from 2% to 5%. Conventional treatment includes conservative and surgical evacuation. Minimally invasive middle meningeal artery (MMA) embolisation is emerging as a potential treatment option. We report our case successfully managed by MMA embolization and review the literature. cSDH development and progression is related to the cycle of chronic inflammation and angiogenesis following the original hemorrhage due to trivial trauma. Due to growth factor, stimulation-initiating angiogenesis leading to growth of leaky blood vessels causing microhaemorrhages resulting in the progressive enlargement of subdural collection as the physiologic absorption capability is outpaced by the rate of collection. Strategies for the management of cSDH are aimed at interrupting the vicious cycle of its development and tilting the balance toward reabsorption of haemorrhage. Conservative management, medical treatment and surgical treatments are conventional treatment options with surgical evacuation considered as the gold standard option. However, challenges include recurrence and reversal of anti-platelets and anti-coagulants and its associated risk of ischaemic complications. cSDH being a pathology of meninges deriving blood the dura causing microhaemorrhages, it is prudent to seal off the vessels to tilt the balance towards resorption. MMA embolisation as a treatment option has been used with significant published data. It may be used as a stand-alone therapy in minimally symptomatic patients. Technical success rate is high both with polyviny alcohol and liquid embolic agents. Recurrence rate is consistently low in spite of significant patients having antiplatelets and anti-coagulants on board. It eliminates the ischemic complication due to stoppage of antiplatelets and anticoagulants. MMA embolization is also emerging as an adjunct to surgically evacuated cSDH that is considered high risk for recurrence.
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