用光电动力学装置定量测定正常和癌变人尿路上皮细胞SMC差异

2018 International Conference on Manipulation, Automation and Robotics at Small Scales (MARSS) Pub Date : 2018-07-01 DOI:10.1109/MARSS.2018.8481192

Ya-Lan Lin, Na Liu, Yang Yang, Shaorong Xie, Liang Dong, Yan Peng, Huayan Pu, P. Chiou, W. J. Li, Yu Sun

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引用次数: 2

摘要

本文报道了利用光电动力学(OEK)装置测量恶性人膀胱癌细胞(RT4)和良性人尿路上皮细胞(sv - huv - 1)的比膜电容(SMC)。实验结果首次表明，RT4细胞(n=54)的SMC明显大于sv - huv - 1细胞(n=48)，为15.8±3.5 mF/m2vs。12.5±2.3 mF/m2，提示SMC可能是鉴别人尿路上皮细胞良恶性的潜在生物标志物，有助于膀胱癌的检测。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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SMC Difference of Normal and Cancerous Human Urothelial Cells Quantified with an Opto-Electrokinetic Device

This paper reports the use of an opto-electrokinetic (OEK) device to measure the specific membrane capacitance (SMC) of malignant human bladder cancer cells (RT4) and benign human urothelial cells (SV-HUV-l). Experimental results, for the first time, show that RT4 cells (n=54) have a significantly larger SMC than SV-HUV-l cells (n=48), 15.8 ± 3.5 mF/m2vs. 12.5 ± 2.3 mF/m2, indicating that SMC could be a potentially useful biomarker for distinguishing malignant and benign human urothelial cells to aid bladder cancer detection.

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来源期刊

2018 International Conference on Manipulation, Automation and Robotics at Small Scales (MARSS)

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