基于石墨烯水门控场效应晶体管的无标签免疫传感器

2019 IEEE 8th International Workshop on Advances in Sensors and Interfaces (IWASI) Pub Date : 2019-06-13 DOI:10.1109/IWASI.2019.8791429

R. Picca, D. Blasi, E. Macchia, K. Manoli, C. Franco, G. Scamarcio, F. Torricelli, A. Zurutuza, Ilargi Napal, A. Centeno, L. Torsi

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引用次数: 2

摘要

电解质门控石墨烯场效应晶体管在这里被提议用于生物传感应用。为此，采用基于该技术的无标记免疫传感器对IgG进行灵敏、选择性的检测。与基于生物受体固定在石墨烯层上的典型方法不同，在这种工作中，由于在金门电极上形成了一层紧密堆积的抗igg受体，因此可以达到低飞摩尔范围的灵敏度。

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A label-free immunosensor based on a graphene water-gated field-effect transistor

Electrolyte-gated graphene field-effect transistors are here proposed for biosensing applications. To this end, a label-free immunosensor based on this technology is employed for the sensitive and selective detection of IgG. Differently from the typical approach based on the bioreceptor immobilization onto a graphene layer, in this work sensitivity in the lower femtomolar range can be reached thanks to the formation of a closely packed layer of anti-IgG receptors anchored to the gold gate electrode.

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2019 IEEE 8th International Workshop on Advances in Sensors and Interfaces (IWASI)

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