基于加权基因共表达网络的技术融合机制分析

Hong Miao, Yan Wang, Lucheng Huang, Feifei Wu, Xin Li
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引用次数: 0

摘要

技术融合是一个具有挑战性的领域中的一个研究热点。分析融合机制,挖掘影响技术融合的关键技术,对引导技术融合发展,提高企业自主创新能力具有重要意义。将基因工程引入技术创新和技术融合的过程是一种新颖的思想,因为它们都具有类似的重组过程。本研究将基于拓扑重叠结构相似性度量的加权基因共表达网络分析(WGCNA)用于专利的国际专利分类(IPC)分析。在本分析中,使用动态树切算法将具有高相关性的基因识别为“技术基因模块”。进而获得与技术融合高度相关且在模块内具有高连通性的枢纽技术基因。该研究揭示了技术之间存在的内在联系,为研究技术融合的融合机制提供了新的思路。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Analysis on Technology Convergence Mechanism using Weighted Gene Co-expression Network
Technology convergence is a hot research topic within a challenging field. It is of great significance to analyze the fusion mechanism and mine the key technologies that affect technology convergence, which can guide the development of technology fusion and improve the independent innovation capability of enterprises. It is a novel idea to introduce genetic engineering into the process of technological innovation and convergence as the similar recombination process they both have. In this study, weighted gene co-expression network analysis (WGCNA), which is based on the similarity measure of a topological overlap structure, was utilized in the analysis of the International Patent Classification (IPC) of patents. In this analysis, the gene with a high correlation was identified as a "technical gene module" using the dynamic tree cut algorithm. Furthermore, hub technology genes, which are highly related to technology fusion and have high connectivity in the module, could be obtained. This study revealed the internal relationships present in technologies and provided novel ideas for researching the fusion mechanism of technology convergence.
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