顺势疗法在治疗慢性甲亢中的作用:一项前测后测介入研究

Gurudev Choubey, Laijun Nahar, Rajib Purkait, A. Banerjee, V. Roja
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引用次数: 1

摘要

摘要背景:慢性甲沟炎(Chronic paronychia, CP)是一种最常见的顽固性指甲疾病,给患者带来了相当大的不适,严重影响了印度次大陆家庭主妇的生活质量(QoL)。目的评价个体化顺势疗法(IHT)在治疗CP患者疼痛发作及改善患者生活质量中的作用。方法对40例CP患者进行前测后测的临床研究,以数值评定量表(NRS)和皮肤病生活质量指数(DLQI)作为预后指标,分别在基线和治疗2个月后进行评估。修订的Naranjo标准(MNC)评估了IHT可能的因果归因。结果两组疼痛NRS评分差异有统计学意义(8.89±0.84 vs 2.97±1.17;95%置信区间[CI] = 5.44-6.39;DLQI评分(19.35±2.95 vs 3.59±1.99;95% ci = 15.06-16.45;P < 0.01)。临床获得的大效应量(4.17)证实了治疗CP疼痛发作的有益效果。MNC评分(7-10)确定了IHT改善的可能性。结论IHT能明显减轻CP引起的疼痛,提高患者的生活质量。有必要采用改进的方法进行进一步的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Role of Homoeopathy in Managing Chronic Paronychia: A Pretest–Posttest Interventional Study
Abstract Background  Chronic paronychia (CP), one of the commonest recalcitrant nail disorders, is a troublesome source of considerable discomfort to the patients, which negatively affects the quality of life (QoL) mainly of the housewives reporting in the Indian subcontinent. Objective  The aim of this study is to assess the utility of individualised homoeopathic treatment (IHT) in managing painful episodes with the improvement in QoL of CP patients. Method  A pretest–posttest clinical study was conducted on 40 patients with CP. The Numeric Rating Scale (NRS) and Dermatology Life Quality Index (DLQI) were the outcome measures, assessed at baseline and after 2 months of IHT. Modified Naranjo Criteria (MNC) evaluated the possible causal attribution of IHT. Results  There was a statistically significant reduction in pain NRS score (8.89 ± 0.84 vs 2.97 ± 1.17; 95% confidence interval [CI] = 5.44–6.39; p  < 0.01) as well as DLQI score (19.35 ± 2.95 vs 3.59 ± 1.99; 95% CI = 15.06–16.45; p  < 0.01) among 37 patients. The large effect size derived (4.17) clinically, substantiates the beneficial effects in managing the painful episodes of CP. The MNC scores (7–10) ascertained the likelihood of improvement due to IHT. Conclusion  IHT significantly reduced the pains due to CP and improved the QoL. Further studies are warranted with enhanced methodology.
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