双层检测器CT虚拟单色图像在头颈部计算机断层扫描中的有效性评价

Mun-Seong Kwon, H. Yu, Chang-Seop Oh, Min Lee, Yong-Sik Bang, Hyeon-Seok Han
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引用次数: 0

摘要

在双能计算机断层扫描(CT)的众多功能中,与传统的迭代重建图像相比,虚拟单色图像提供了多种诊断价值,例如根据单色图像水平增加血管内碘的可视化或减少光束硬化伪影。诊断的最佳单色图像水平对每个应用的解剖部位是不同的,在颈部CT方案中,我们打算通过定量方法找到诊断的最佳虚拟单色图像水平。我们回顾性研究了33例采用双层检测器型IQon光谱CT (Philips, Amsterdam, Netherlands)的患者。评估部位为颈总动脉、颈内静脉、胸锁乳突肌、下颌下腺和甲状腺。作为图像评价指标,采用以胸锁乳突肌为背景设置的信噪比(CNR)公式。比较了IMR和iDose迭代重建图像和40 ~ 100 keV的单色图像,图像间隔为10 keV。在对数据进行正态性检验以检验比较图像的均值是否存在显著性差异后,进行非参数响应样本检验Friedman检验,所有数据之间均存在显著性差异。结果表明,在单色40 keV图像中,除胸锁乳突肌外,所有评价部位的信噪比和CNR均最高。与现有临床试验中使用的迭代重建图像相比,单色40 keV图像有望通过提供更好的图像质量和更高的定量对比度来帮助诊断,并提供减少研究中使用造影剂量的可能性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Usefulness Assessment of Virtual Monochromatic Image using Dual Layer Detector CT in Head & Neck Computed Tomography
Among the many functions of dual-energy computed tomography (CT), virtual monochromatic images provide various diagnostic values compared to conventional iterative reconstruction images, such as increasing visualization of intravascular iodine or reducing beam hardening artifact according to monochromatic image level. The optimal monochromatic image level for diagnosis differs for each applied anatomical site, In the neck CT protocol, we intend to find the optimal level of virtual monochromatic images for diagnosis through quantitative methods. We retrospectively studied 33 patients performed on dual layer detector type IQon Spectral CT (Philips, Amsterdam, Netherlands). The evaluation site was designated as the common carotid artery, internal jugular vein, sternocleidomastoid muscle, submandibular glands, and thyroid glands. As an indicator of image evaluation, the contrast-to-noise ratio (CNR) formula set against the background of sternocleido-mastoid muscle and signal-to-noise ratio (SNR) was used. The IMR and iDose iterative reconstruction images and the monochromatic Images 40 keV to 100 keV with the images at intervals of 10 keV were compared. After the normality test of the data was performed to check whether there was a significant difference in the mean of the comparative images, the Friedman test, a nonparametric response sample test, was performed, and all data were significantly different from each other. As a result of the experiment, SNR and CNR were measured the highest in the monochromatic 40 keV image of all evaluation sites except the sternocleido-mastoid muscle. Monochromatic 40 keV image is expected to help diagnose by providing better image quality and higher contrast in quantitative terms than the iterative reconstruction images used in existing clinical trials, and provides the possibility of reducing the amount of contrast medium used in the study.
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