一种模拟蛋白质折叠过程的新方法——Snake算法

J. Zhang, Maozu Guo, Song-Bo Li, Wei Peng
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引用次数: 3

摘要

蛋白质折叠过程的研究是蛋白质研究领域的一个难题。本文提出了一种新的仿真算法——蛇形仿真算法来解决这一问题。为了证明蛇仿真算法中关键功能的正确性和可行性,应用了分子振荡理论和分子动力学理论。此外,提出了一个描述蛋白质折叠过程的模型,得出所有的蛋白质结构都可以通过两类函数来构建。与其他五种蛋白质折叠算法相比,蛇模拟算法在能量和蛋白质结构相似性方面具有很大的优势。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A New Method for Simulating Protein Folding Process -- Snake Algorithm
It is a difficult problem of studying the protein folding process in the protein research field. In this paper, a new simulation algorithm-snake simulation algorithm is put forward to solve the problem. In order to prove the key function in snake simulation algorithm is correct and feasible, theory of molecule oscillation and molecule kinetics are used. In addition, bring forward a model that describes the process of protein folding, concludes that all the protein structure can be constructed by two type functions. Compared with other five protein folding algorithms, the snake simulation algorithm has a great advantage in the energy and similar of protein structure.
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