{"title":"转基因蚊子——是福还是祸","authors":"Nidhi Sharma, S. Jain","doi":"10.15406/jig.2018.05.00074","DOIUrl":null,"url":null,"abstract":"In 1870 the discoveries of Pasteur and Koch had precipitated a search for a bacterial cause for many diseases including malaria. In 1880, Laveran meticulously examined the blood of 200patients and in 148 observed the crescentic bodies in all cases of malaria but never in those without malaria. He also noted that quinine removed these stages from the blood. Laveran quickly realized that he had found a parasitic protozoan which he called Oscillariamalariae.5 In initial 19th century, it was known that malaria was caused by a protozoan parasite that invaded and multiplied in red blood cells and, after a lot of confusion, that there were three species with specific periodicities and other characteristics responsible for benign tertian (Haemamoebavivax), malignant tertian (Laveraniamalariae) and quartan (Haemamoebamalariae) malaria now respectively Plasmodium vivax, P. falciparum and P. malariae.6","PeriodicalId":260490,"journal":{"name":"Journal of Investigative Genomics","volume":"50 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2018-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Genetically modified Mosquitoes-blessing or curse\",\"authors\":\"Nidhi Sharma, S. Jain\",\"doi\":\"10.15406/jig.2018.05.00074\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In 1870 the discoveries of Pasteur and Koch had precipitated a search for a bacterial cause for many diseases including malaria. In 1880, Laveran meticulously examined the blood of 200patients and in 148 observed the crescentic bodies in all cases of malaria but never in those without malaria. He also noted that quinine removed these stages from the blood. Laveran quickly realized that he had found a parasitic protozoan which he called Oscillariamalariae.5 In initial 19th century, it was known that malaria was caused by a protozoan parasite that invaded and multiplied in red blood cells and, after a lot of confusion, that there were three species with specific periodicities and other characteristics responsible for benign tertian (Haemamoebavivax), malignant tertian (Laveraniamalariae) and quartan (Haemamoebamalariae) malaria now respectively Plasmodium vivax, P. falciparum and P. malariae.6\",\"PeriodicalId\":260490,\"journal\":{\"name\":\"Journal of Investigative Genomics\",\"volume\":\"50 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-08-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Investigative Genomics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15406/jig.2018.05.00074\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Investigative Genomics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15406/jig.2018.05.00074","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
In 1870 the discoveries of Pasteur and Koch had precipitated a search for a bacterial cause for many diseases including malaria. In 1880, Laveran meticulously examined the blood of 200patients and in 148 observed the crescentic bodies in all cases of malaria but never in those without malaria. He also noted that quinine removed these stages from the blood. Laveran quickly realized that he had found a parasitic protozoan which he called Oscillariamalariae.5 In initial 19th century, it was known that malaria was caused by a protozoan parasite that invaded and multiplied in red blood cells and, after a lot of confusion, that there were three species with specific periodicities and other characteristics responsible for benign tertian (Haemamoebavivax), malignant tertian (Laveraniamalariae) and quartan (Haemamoebamalariae) malaria now respectively Plasmodium vivax, P. falciparum and P. malariae.6