肺表面活性剂扩散过程中的斑点

J. J. Llovera-González, Alfredo B. Moreno-Yeras, Diana M. Martínez-Muñoz, M. Z. J. Ferreira, Wagner Shin Nishitani, Alexandre Barros Almeida, A. Alencar, M. Muramatsu, Rolando L. Serra-Toledo
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引用次数: 0

摘要

肺表面活性物质是治疗新生儿呼吸功能不全综合征的重要药物。在实验室中合成这种表面活性剂需要优化在肺泡间质液中的扩散速度,从而获得一层磷脂膜基,能够在呼吸过程中维持呼吸系统的一些动力学特性。这些机械性能的恢复必须使用最少量的产品和最佳的蛋白质组成(特别是SP-B)进行存档。本文展示了在存在生理性间质液时,制备和处理由该产物(DPPC)基质组成的磷脂膜的散斑图像的结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Speckle patterns during the spreading of lung surfactant
Pulmonary surfactant is a very important product in the medical treatment of the syndrome of insufficiency respiratory in neonates. The synthesis of this surfactant in labs need to optimize the rate of spreading in the alveolar interstitial liquid obtaining a monolayer of the phospholipids membrane base capable to maintains several of the dynamical properties of the respiratory system during breathing. The recover of theses mechanical properties has to be archived using the minimal quantities of product and with the optimal proteins composition (SP-B in special). In this paper we show our results of obtaining and process speckle pattern images of the spreading of phospholipids membrane composed the matrix of this product (DPPC) when physiologic interstitial liquid are presented.
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