Mahshid Deldar Abad Paskeh, Z. Salehi, A. Ghayeghran
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Investigation of the Relationship Between Polymorphism in miR-34b/c and Risk of Alzheimer's Disease
: The significant role of microRNAs (miRNAs) in gene expression regulation has been demonstrated. Changes in the expression of miRNAs have been reported in a variety of neurological diseases. However, the role of miR-34b/c in the risk of Alzheimer's disease has been less studied. Therefore, the current study aims to investigate the relationship between miR-34b/c polymorphism and the risk of Alzheimer's disease. This study was performed with 40 Alzheimer's patients and 40 controls. Using the polymerase chain reaction technique to investigate polymorphisms in the miR-34b/c gene. The results of this study indicated an association between miR-34 b/c polymorphisms and the risk of Alzheimer's disease.
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